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25316-40-9

25316-40-9 Structure

25316-40-9 Structure
IdentificationMore
【Name】

Doxorubicin hydrochloride
【CAS】

25316-40-9
【Synonyms】

14-HYDROXYDAUNOMYCIN HCL
14-HYDROXYDAUNOMYCIN HYDROCHLORIDE
(8s-cis)-10-[(3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxynaphthacene-5,12-dione hydrochloride
ADRIACIN
ADRIAMYCIN
ADRIAMYCIN HCL
ADRIAMYCIN HYDROCHLORIDE
ADRIBLASTINA
ADRIBLASTINA HYDROCHLORIDE
CAELYX
DOX HYDROCHLORIDE
DOXORUBICIN HCL
DOXORUBICIN HYDROCHLORIDE
HYDROXYDAUNORUBICIN HYDROCHLORIDE
(8s-cis)-hlorid
10-((3-amino-2,3,6-trideoxy-alpha-l-lyxo-hexopyranosyl)oxy)-7,8,9,10-tetrahydro-12-naphthacenedione
8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-xy)-hydroc
admhydrochloride
Ardriamycin
fi6804
【EINECS(EC#)】

246-818-3
【Molecular Formula】

C27H30ClNO11
【MDL Number】

MFCD00077757
【Molecular Weight】

579.98
【MOL File】

25316-40-9.mol
Chemical PropertiesBack Directory
【Appearance】

Orange-Red Crystalline Solid
【mp 】

216 °C (dec.)(lit.)
【storage temp. 】

2-8°C
【solubility 】

H2O: 10 mg/mL, clear, red-orange
【Usage】

Used as an antineoplastic
【Merck 】

13,3473
【CAS DataBase Reference】

25316-40-9(CAS DataBase Reference)
【EPA Substance Registry System】

25316-40-9(EPA Substance)
Safety DataBack Directory
【Hazard Codes 】

T,T+
【Risk Statements 】

R45:May cause cancer.
R22:Harmful if swallowed.
R40:Limited evidence of a carcinogenic effect.
R26/27/28:Very Toxic by inhalation, in contact with skin and if swallowed .
【Safety Statements 】

S53:Avoid exposure - obtain special instruction before use .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S22:Do not breathe dust .
S7/9:Keep container tightly closed and in a well-ventilated place .
【WGK Germany 】

3
【RTECS 】

QI9295900
【F 】

10-21
Raw materials And Preparation ProductsBack Directory
【Raw materials】

Daunorubicin
【Preparation Products】

Pirarubicin
Hazard InformationBack Directory
【General Description】

Orange-red thin needles. Aqueous solutions yellow-orange at acid pHs, orange-red at neutral pHs, and violet blue over pH 9.
【Reactivity Profile】

Amines, like ADRIAMYCIN HYDROCHLORIDE(25316-40-9), are weak chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides.
【Air & Water Reactions】

Water soluble.
【Fire Hazard】

This compound is probably combustible.
Material Safety Data Sheet(MSDS)Back Directory
【msds information】

(8S-cis)-10-[(3-Amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxynaphthacene-5,12-dione hydrochloride(25316-40-9).msds
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