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Quinupristin

Quinupristin Suppliers list
Company Name:J & K SCIENTIFIC LTD.  
Tel:400-666-7788 +86-10-82848833
Email:jkinfo@jkchemical.com;market3@jkchemical.com
Products Intro: Product Name:Quinupristin Discontinued
CAS:120138-50-3
Package:500Mg,50Mg
Company Name:Chembest Research Laboratories Limited  
Tel:+86(0)21-20908456
Email:sales@biochembest.com
Products Intro: Product Name:Quinupristin(RP-57669)
CAS:120138-50-3
Remarks:C14819
Company Name:Chemsky (shanghai) International Co.,Ltd  
Tel:021-50135380
Email:shchemsky@sina.com
Products Intro: Product Name:Quinupristin;4-[4-(DiMethylaMino)-N-Methyl-L-phenylalanine]-5-[(2S,5R)-5-[[[(3S)-1-azabicyclo[2.2.2]oct-3-yl]thio]Methyl]-4-oxo-2-piperidinecarboxylic acid]virginiaMycin S1; Antibiotic RP 57669; RP 57669; RP 68888
CAS:120138-50-3
Purity:98+% Package:1Mg;5Mg;10Mg;50Mg;100Mg;500Mg
Company Name:ChemStrong Scientific Co.,Ltd  
Tel:0755 66853366
Email:sales@chem-strong.com;
Products Intro: Product Name:Quinupristin mesylate
CAS:120138-50-3
Purity:>98% by HPLC Package:1mg,5mg
Quinupristin Basic information
Product Name:Quinupristin
Synonyms:4-[4-(DiMethylaMino)-N-Methyl-L-phenylalanine]-5-[(2S,5R)-5-[[[(3S)-1-azabicyclo[2.2.2]oct-3-yl]thio]Methyl]-4-oxo-2-piperidinecarboxylic acid]virginiaMycin S1;Antibiotic RP 57669;RP 57669;RP 68888;Quinupristin(RP-57669);Quinupristin Discontinued;Quinupristin Mesylate
CAS:120138-50-3
MF:C53H67N9O10S
MW:1022.23
EINECS:
Product Categories:Amino Acids & Derivatives;Aromatics;Chiral Reagents;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals
Mol File:120138-50-3.mol
Quinupristin Structure
Quinupristin Chemical Properties
Safety Information
MSDS Information
Quinupristin Usage And Synthesis
UsageSemisynthetic depsipeptide type I streptogramin. An antibacterial agent.
UsageQuinupristin is a semi-synthetic analogue of virginiamycin B (ostreogyrcin B, pristinamycin IA, streptogramin B) formed by a Mannich condensation and elimination to generate an exocyclic methylene alpha to the ketone of the 4-piperidinone. Addition of quinucidinylthiol to the methylene group affords quinupristin. The structural changes provide a more hydrophobic compound with a readily ionisable group for generating a salt. Quinupristin is used commercially in synergistic combination with dalfopristin (30:70). There is little published data on the synthesis, biological or antibiotic activity of quinupristin alone, however the combination product is highly effective, including activity against antibiotic resistant strains.
UsageQuinupristin is a semi-synthetic analogue of virginiamycin B (ostreogrycin B, pristinamycin IA, streptogramin B) formed by a Mannich condensation and elimination to generate an exocyclic methylene alpha to the ketone of the 4-piperidinone. Addition of quinucidinylthiol to the methylene group affords quinupristin. The structural changes provide a more hydrophobic compound with a readily ionisable group for generating a salt. Quinupristin is used commercially in synergistic combination with dalfopristin (30:70). There is little published data on the synthesis, biological or antibiotic activity of quinupristin alone, however the combination product is highly effective, including activity against antibiotic resistant strains.
Quinupristin Preparation Products And Raw materials
Tag:Quinupristin(120138-50-3) Related Product Information
4-[N-Methyl-4-(methylamino)-L-phenylalanine]virginiamycin S1 2-AMINO-1-PIPERIDIN-1-YL-ETHANONE HCL (1-ETHYL-2-PIPERIDINYL)-N-METHYLMETHANAMINE AC-ALA-ALA-ALA-ALA-OME N-methylpiperidine-2-carboxamide ETHYL[(1-ETHYLPIPERIDIN-2-YL)METHYL]AMINE 2-(2-methylpiperidin-1-yl)ethanamine N-(1-phenylethyl)piperidine-2-carboxamide ETHYL[(1-PROPYLPIPERIDIN-2-YL)METHYL]AMINE Quinupristin-dalfopristin ISO-BUTYL ISO-PROPYL SULFIDE CHEMBRDG-BB 9070682 1-ethylpiperidine-2-methylamine Methyl[(1-methylpiperidin-2-yl)methyl]amine ETHYL[(1-METHYLPIPERIDIN-2-YL)METHYL]AMINE 1-butyrylpiperidin-4-one N-Acetyl-4-piperidone C-(1-METHYL-PIPERIDIN-2-YL)-METHYLAMINE