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GDC-0068

GDC-0068 Suppliers list
Company Name:Shanghai Boyle Chemical Co., Ltd.  
Tel:Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)
Email:sales@boylechem.com
Products Intro: Product Name:GDC-0068
CAS:1001264-89-6
Purity:98%min Package:100G,1KG.5KG
Company Name:J & K SCIENTIFIC LTD.  
Tel:400-666-7788 +86-10-82848833
Email:jkinfo@jkchemical.com;market3@jkchemical.com
Products Intro: Product Name:(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-Methyl-5H-cyclopentapyriMidin-4-yl]-1-piperazinyl]-3-[(1-Methylethyl)aMino]-1-propanone
CAS:1001264-89-6
Package:10Mg,50Mg,5Mg
Company Name:Chembest Research Laboratories Limited  
Tel:+86(0)21-20908456
Email:sales@biochembest.com
Products Intro: Product Name:GDC-0068(RG7440)
CAS:1001264-89-6
Remarks:C13704
Company Name:JinYan Chemicals(ShangHai) Co.,Ltd.  
Tel:13817811078,021-50426030
Email:sales@jingyan-chemical.com
Products Intro: Product Name:NA
Company Name:Shanghai Science Bio-Pharmaceutical Co. Ltd.  
Tel:021-57872719,13918702962/13482412995
Email:market@freefluor.com
Products Intro: Product Name:GDC-0068
CAS:1001264-89-6
Package:5Mg;10Mg;25Mg;50Mg
GDC-0068 Basic information
Product Name:GDC-0068
Synonyms:GDC-0068;GDC-0068(RG7440);RG7440;(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone;Ipatasertib (GDC-0068);Ipatasertib;(S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one;(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone Ipatasertib (GDC-0068)
CAS:1001264-89-6
MF:C24H32ClN5O2
MW:457.99618
EINECS:
Product Categories:Inhibitor;PI3K/Akt/mTOR
Mol File:1001264-89-6.mol
GDC-0068 Structure
GDC-0068 Chemical Properties
density 1.254
Safety Information
MSDS Information
GDC-0068 Usage And Synthesis
UsageDC-0068 is a highly selective pan-Akt inhibitor targeting Akt1, Akt2, and Akt3 with IC50 of 5 nM, 18 nM, and 8 nM, respectively.
Usage(2S)-2-(4-Chlorophenyl)-1-[4-[(5R,7R)-6,7-dihydro-7-hydroxy-5-methyl-5H-cyclopentapyrimidin-4-yl]-1-piperazinyl]-3-[(1-methylethyl)amino]-1-propanone is a highly selective AKT inhibitor targeting Akt1 , Akt2 and Akt3. Studies have shown its use in combination with vemurafenib (V118500), have demonstrated therapeutic value in the treatment of hyperproliferative disorders such as cancer.
GDC-0068 Preparation Products And Raw materials
Tag:GDC-0068(1001264-89-6) Related Product Information
4-[2-(4-Amino-1,2,5-oxadiazol-3-yl)-1-ethyl-7-[(3S)-3-piperidinylmethoxy]-1H-imidazo[4,5-c]pyridin-4-yl]-2-methyl-3-butyn-2-ol MK-2206 2HCl (2S)-N1-[4-Methyl-5-[2-(2,2,2-trifluoro-1,1-dimethylethyl)-4-pyridinyl]-2-thiazolyl]-1,2-pyrrolidinedicarboxamide Pictilisib (GDC-0941) AZD5363 Rapamycin