| Company Name: | 3B Pharmachem (Wuhan) International Co.,Ltd. |
| Tel: | 86-21-50328103 * 801、802、803、804 Mobile:18930552037 |
| Email: | 67055399@qq.com |
| Products Intro: |
Product Name:SB 224289 hydrochloride;1'-Methyl-5-[[2'-Methyl-4'-(5-Methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]carbonyl]-2,3,6,7-tetrahydrospiro[furo[2,3-f]indole-3,4'-piperidinehydrochloride
CAS:180083-23-2
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g |
| Company Name: | Nanjing Chemlin Chemical Co., Ltd |
| Tel: | 025-83697070; 010-68547217 |
| Email: | sales@chemlin.com.cn |
| Products Intro: |
Product Name:SB 224289 HCl
CAS:180083-23-2
Purity:97% |
| Company Name: | ShangHai Biochempartner Co.,Ltd |
| Tel: | +86 13818785766，400-021-9906 |
| Email: | gaoqing@biochempartner.com |
| Products Intro: |
Product Name:SB 224289 hydrochloride
CAS:180083-23-2
Purity:99% Package:10Mg 50Mg 100Mg 1g 5g 10g |
| Company Name: | BOC Sciences |
| Tel: | 1-631-504-6093 |
| Email: | sales@bocsci.com |
| Products Intro: |
Product Name:1'-METHYL-5-[[2'-METHYL-4'-(5-METHYL-1,2,4-OXADIAZOL-3-YL)BIPHENYL-4-YL]CARBONYL]-2,3,6,7-TETRAHYDROSPIRO[FURO[2,3-F]INDOLE]-3,4'-PIPERIDINE HYDROCHLORIDE
CAS:180083-23-2
|
| Company Name: | Chengdu NoVi Biotechnology Co., Ltd. |
| Tel: | 028-81458053；13551243286；QQ：987166710 |
| Email: | novibiotech@163.com sales@novi-biotech.com |
| Products Intro: |
Product Name:1'-METHYL-5-[[2'-METHYL-4'-(5-METHYL-1,2,4-OXADIAZOL-3-YL)BIPHENYL-4-YL]CARBONYL]-2,3,6,7-TETRAHYDROSPIRO[FURO[2,3-F]INDOLE]-3,4'-PIPERIDINE HYDROCHLORIDE
CAS:180083-23-2
Purity:98% HPLC Package:100Mg;500Mg;1g;5g;10g;20g;50g Remarks:NV02060 |
|
| | 1'-METHYL-5-[[2'-METHYL-4'-(5-METHYL-1,2,4-OXADIAZOL-3-YL)BIPHENYL-4-YL]CARBONYL]-2,3,6,7-TETRAHYDROSPIRO[FURO[2,3-F]INDOLE]-3,4'-PIPERIDINE HYDROCHLORIDE Basic information |
| Product Name: | 1'-METHYL-5-[[2'-METHYL-4'-(5-METHYL-1,2,4-OXADIAZOL-3-YL)BIPHENYL-4-YL]CARBONYL]-2,3,6,7-TETRAHYDROSPIRO[FURO[2,3-F]INDOLE]-3,4'-PIPERIDINE HYDROCHLORIDE | | Synonyms: | 1'-METHYL-5-[[2'-METHYL-4'-(5-METHYL-1,2,4-OXADIAZOL-3-YL)BIPHENYL-4-YL]CARBONYL]-2,3,6,7-TETRAHYDROSPIRO[FURO[2,3-F]INDOLE]-3,4'-PIPERIDINE HYDROCHLORIDE;6,7-DIHYDRO-1'-METHYL-5-[[2'-METHYL-4'-(5-METHYL-1,2,4-OXADIAZOL-3-YL)[1,1'-BIPHENYL]-4-YL]CARBONYL]-SPIRO[2H-FURO[2,3-F]INDOLE-3(5H) HYDROCHLORIDE;SB 224,289 HYDROCHLORIDE;1Methyl-5-((2methyl-4(5-methyl-1,2,4-oxadiazol-3-yl)biphenyl-4-yl)carbonyl)-2,3,6,7-tetrahydrospiro(furo[2.3-f]ind;SB224289HCl;[2'-Methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-yl](2,5,6,7-tetrahydro-1'-methylspiro[3H-furo[2,3-f]indole-3,4'-piperidin]-5-yl)methanone;SB 224289;(2'-Methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-[1,1'-biphenyl]-4-yl)(1'-methyl-6,7-dihydrospiro[fu | | CAS: | 180083-23-2 | | MF: | C32H33ClN4O3 | | MW: | 557.08 | | EINECS: | | | Product Categories: | | | Mol File: | 180083-23-2.mol | ![1'-METHYL-5-[[2'-METHYL-4'-(5-METHYL-1,2,4-OXADIAZOL-3-YL)BIPHENYL-4-YL]CARBONYL]-2,3,6,7-TETRAHYDROSPIRO[FURO[2,3-F]INDOLE]-3,4'-PIPERIDINE HYDROCHLORIDE Structure](CAS\GIF\180083-23-2.gif) |
| | 1'-METHYL-5-[[2'-METHYL-4'-(5-METHYL-1,2,4-OXADIAZOL-3-YL)BIPHENYL-4-YL]CARBONYL]-2,3,6,7-TETRAHYDROSPIRO[FURO[2,3-F]INDOLE]-3,4'-PIPERIDINE HYDROCHLORIDE Chemical Properties |
| mp | >280℃ | | density | 1.34 | | storage temp. | Store at RT | | solubility | DMSO: 4.5 mg/mL
| | form | solid
| | color | off-white
|
| | 1'-METHYL-5-[[2'-METHYL-4'-(5-METHYL-1,2,4-OXADIAZOL-3-YL)BIPHENYL-4-YL]CARBONYL]-2,3,6,7-TETRAHYDROSPIRO[FURO[2,3-F]INDOLE]-3,4'-PIPERIDINE HYDROCHLORIDE Usage And Synthesis |
| Biological Activity | Selective 5-HT 1B receptor antagonist (pK i = 8.2). Displays > 60-fold selectivity over 5-HT 1D , 5-HT 1A , 5-HT 1E , 5-HT 1F , 5-HT 2A and 5-HT 2C receptors in radioligand binding and functional assays. Centrally active following oral administration in vivo . |
| | 1'-METHYL-5-[[2'-METHYL-4'-(5-METHYL-1,2,4-OXADIAZOL-3-YL)BIPHENYL-4-YL]CARBONYL]-2,3,6,7-TETRAHYDROSPIRO[FURO[2,3-F]INDOLE]-3,4'-PIPERIDINE HYDROCHLORIDE Preparation Products And Raw materials |
|