| Company Name: | J & K SCIENTIFIC LTD. |
| Tel: | 400-666-7788 +86-10-82848833 |
| Email: | jkinfo@jkchemical.com;market3@jkchemical.com |
| Products Intro: |
Product Name:Iloprost
CAS:78919-13-8
Package:0.25Mg,2.5Mg |
| Company Name: | Chemvon Biotechnology Co., Ltd |
| Tel: | +86-21-50790412 |
| Email: | marketing@chemvon.com |
| Products Intro: |
Product Name:Iloprost
CAS:78919-13-8
Purity:99% Package:1g, 10g, 100g, 200g, 1kg, 5kg |
| Company Name: | 3B Pharmachem (Wuhan) International Co.,Ltd. |
| Tel: | 86-21-50328103 * 801、802、803、804 Mobile:18930552037 |
| Email: | 67055399@qq.com |
| Products Intro: |
Product Name:Iloprost;(5E)-5-[(3aS,4R,5R,6aS)-Hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-Methyl-1-octen-6-ynyl]-2(1H)-pentalenylidene]pentanoicacid
CAS:78919-13-8
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g |
| Company Name: | LGM Pharma |
| Tel: | 1-(800)-881-8210 |
| Email: | inquiries@lgmpharma.com |
| Products Intro: |
Product Name:Iloprost
CAS:78919-13-8
Purity:Typically NLT 98% |
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| | ILOPROST Basic information |
| Product Name: | ILOPROST | | Synonyms: | (16r,s)-methyl-18,18,19,19-tetradehydro-6a-carbaprostaglandini(sub2);1h)-pentalenylidene)-;pentanoicacid,5-(hexahydro-5-hydroxy-4-(3-hydroxy-4-methyl-1-octen-6-ynyl)-2(;zk36374;6,9ALPHA-METHYLENE-11ALPHA,15S-DIHYDROXY-16-METHYL-PROSTA-5E,13E-DIEN-18-YN-1-OIC ACID;CILOPROST;5-[Hexahydro-5-hydroxy-4-(3-hydroxy-4-methyl-1-octen-6-ynyl)-2(1H)-pentalenylidene]pentanoic acid;Endoprost | | CAS: | 78919-13-8 | | MF: | C22H32O4 | | MW: | 360.49 | | EINECS: | | | Product Categories: | Chiral Reagents;Inhibitors;Intermediates & Fine Chemicals;Pharmaceuticals | | Mol File: | 78919-13-8.mol |  |
| | ILOPROST Chemical Properties |
| storage temp. | Desiccate at -20°C |
| | ILOPROST Usage And Synthesis |
| Chemical Properties | Colourless Oil | | Usage | A synthetic analogue of Prostacyclin (PGI2) used to treat pulmonary arterial hypertension (PAH), scleroderma, Raynaud's phenomenon and ischemia. It acts through elevation of cAMP by binding to the prostacyclin receptor (IP receptor). Iloprost inhibits the ADP, thrombin, and collagen-induced aggregation of human platelets with an ED50 of about 13 nM. In whole animals, iloprost acts as a vasodilator, hypotensive, antidiuretic, and prolongs bleeding time. | | Biological Activity | Prostacyclin (PGI 2 ) analog that binds with high affinity to IP, EP 1 and EP 3 receptors (K i values are 11, 11, 56, 284, 619, 1035, 1870 and 6487 nM for IP, EP 1 , EP 3 , EP 4 , FP, DP, EP 2 and TP receptors respectively). Inhibits platelet aggregation induced by collagen, thrombin and ADP (IC 50 values are 0.24, 0.71 and 1.07 nM respectively). |
| | ILOPROST Preparation Products And Raw materials |
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