GW843682, 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide

CAS番号.	660868-91-7
化学名:
别名:
英語化学名:	GW843682, 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide
英語别名:	GW843682;GW843682X;Polo-like Kinase Inhibitor III;5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide;3-(2-(Trifluoromethyl)benzyloxy)-5-(5,6-dimethoxy-1H-benzo[d]imidazol-1-yl)thiophene-2-carboxamide;5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]-2-thiophenecarboxamide;GW843682, 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide
CBNumber:	CB82090977
分子式:	C22H18F3N3O4S
分子量:	477.461
MOL File:	660868-91-7.mol

GW843682, 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide 物理性質

貯蔵温度 :

2-8°C

安全性情報

主な危険性 :

Rフレーズ :

36/37/38

Sフレーズ :

26-36/37

GW843682, 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide 化学特性,用途語,生産方法

生物活性
Selective inhibitor of polo-like kinase 1 (PLK1) and polo-like kinase 3 (PLK3) (IC 50 values are 2.2 and 9.1 nM respectively). Displays > 100-fold selectivity over ~30 other kinases tested including cdk1 and cdk2. Inhibits proliferation of most tumor cells in vitro and is selective over normal diploid fibroblasts.

GW843682, 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide 上流と下流の製品情報

原材料

準備製品

GW843682, 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide 生産企業 Global( 22)Suppliers

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3B Pharmachem (Wuhan) International Co.,Ltd.	86-21-50328103 * 801、802、803、804 Mobile:18930552037	86-21-50328109	67055399@qq.com	CHINA	15983	69
Shanghai Kuanghao Chemistry Technology Co., Ltd.	021-37285271	021-37285512	sales@kuanghaochem.com	CHINA	68	57
Hangzhou Sage Chemical Co., Ltd.	0571-86818502	Pls mail us for more information!	info@sagechem.com	CHINA	10286	58
NCE Biomedical Co.,Ltd.	4000-027-021 \|24 hour enquiry :+86-13986109188 \|English:+86-15623472865 \|Japanese:+81-08033611988	+86-27-87599188	sales@ncebiomed.com	CHINA	1503	55
Shanghai T&W Pharmaceutical Co., Ltd.	+86 21 61551611	+86 21 50676805	contact@trustwe.com	CHINA	9988	58
Shanghai Haoyuan Chemexpress Co., Ltd	86-21-58998590	86-21-53700326, 86-21-58998590	sales@chemexpress.cn	CHINA	10011	61
Shanghai Aladdin Bio-Chem Technology Co.,LTD	021-20337333/400-620-6333	021-50323701	sale@aladdin-e.com	CHINA	24330	65
MedChemexpress LLC	609-228-6898	609-228-5909	sales@medchemexpress.cn	USA	4935	58
AdooQ BioScience, LLC	+1 (866) 930-6790	+1 (866) 333-9607	info@adooq.com	USA	2786	58
AdooQ Bioscience CHINA	400-025-6535	025-68650336	info@adooq.cn	CHINA	2299	60

660868-91-7(GW843682, 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide) キーワード:

660868-91-7 GW843682, 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide GW843682X 3-(2-(Trifluoromethyl)benzyloxy)-5-(5,6-dimethoxy-1H-benzo[d]imidazol-1-yl)thiophene-2-carboxamide Polo-like Kinase Inhibitor III 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-{[2-(trifluoromethyl)-benzyl]oxy}thiophene-2-carboxamide 5-(5,6-Dimethoxy-1H-benzimidazol-1-yl)-3-[[2-(trifluoromethyl)phenyl]methoxy]-2-thiophenecarboxamide GW843682