Eltrombopag

CAS番号.	496775-61-2
化学名:
别名:
英語化学名:	Eltrombopag
英語别名:	Sb497115;Promacta;Sb-497115;Eltrombopag;Unii-S56D65xj9g;Eltrombopag Acid;Eltrombopag [inn];EltroMbopag (SB-497115-GR);(Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-;(E)-3\'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2\'-hydroxybiphenyl-3-carboxylic acid
CBNumber:	CB71463423
分子式:	C25H22N4O4
分子量:	442.47
MOL File:	496775-61-2.mol

Eltrombopag 物理性質

融点 :

242-244°C

比重(密度) :

1.33

貯蔵温度 :

-20°C Freezer, Under Inert Atmosphere

安全性情報

Eltrombopag 化学特性,用途語,生産方法

化学的特性
Orange to Red Solid

使用
Eltrombopag (SB-497115-GR, Promacta, Revolade) is a small molecule agonist of the c-mpl (TpoR) receptor with an IC50 of 0.69 μM for the inhibition of hERG K+ channel tail current. In preclinical studies, the compound was shown to interact selectively with

使用
An agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia

Eltrombopag 上流と下流の製品情報

原材料

準備製品

Eltrombopag 生産企業 Global( 78)Suppliers

名前	電話番号	ファックス番号	電子メール	国籍	製品カタログ	優位度
ZHIWE CHEMTECH CO LTD	021-20221225;13917446399；QQ:2381298399		sales@zhiwe.net;zwchem@163.com	CHINA	297	61
Shanghai Boyle Chemical Co., Ltd.	Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)	86-21-57758967	sales@boylechem.com	CHINA	5604	55
J & K SCIENTIFIC LTD.	--	--	jkinfo@jkchemical.com;market3@jkchemical.com	CHINA	96847	76
Chembest Research Laboratories Limited	+86(0)21-20908456	+86(0)21-58180499	sales@biochembest.com	CHINA	6000	61
JinYan Chemicals(ShangHai) Co.,Ltd.	13817811078,021-50426030	86-021-50426522,50426273	sales@jingyan-chemical.com	CHINA	10108	60
Jia Xing Isenchem Co.,Ltd	0573-85280080 18267390595	0573-85285100	isenchem@163.com,QQ:1404038297	CHINA	9788	66
Anhui Lianchuang Pharmaceutical chemistry CO.,LTD	0551-68596228 0551-68779238	0551-68596338	sales@lcywhx.com	CHINA	252	57
Chemfun Medical Technology(Shanghai) Co., Ltd.	021-67220633 & 021-37212706	+86-21-67220638	chemfun@chemfun.net	CHINA	21915	59
LGM Pharma	1-(800)-881-8210	615-250-9817	inquiries@lgmpharma.com	USA	1972	70
Nanjing Chemlin Chemical Co., Ltd	025-83697070; 010-68547217	+86-25-83453306	sales@chemlin.com.cn	CHINA	20120	64

496775-61-2(Eltrombopag) キーワード:

[1,2-フェニレンビス(イミノカルボノチオイル)]ビス(カルバミド酸)ジメチル 4-ヒドロキシ安息香酸メチル N,N-ジメチルアセトアミド N,N-ジメチルホルムアミド 1-(4,6-ジメトキシピリミジン-2-イル)-3-[[2-(メトキシカルボニル)ベンジル]スルホニル]尿素 1,5-ジフェニルカルボノヒドラジド 1,2-ジメチルヒドラジン二塩酸塩チオりん酸ジメチル=4-ニトロフェニルジメチルスルホン 2-チオフェンカルボン酸メチル 2,6-ジメチル-7-オクテン-2-オールクロロジメチルフェニルシランクレソキシムメチルジメチルスルホキシドアクリル酸メチルブロモメタンシリコーンゴム

496775-61-2 Eltrombopag 3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid (1,1'-Biphenyl)-3-carboxylic acid, 3'-((2Z)-(1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene)hydrazino)-2'-hydroxy- Eltrombopag [inn] Promacta Sb497115 Sb-497115 Unii-S56D65xj9g (E)-3\'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2\'-hydroxybiphenyl-3-carboxylic acid 3-(5-{2-[2-(3,4-diMethylphenyl)-5-Methyl-3-oxo-2,3-dihydro-1H-pyrazol-4-yl]hydrazin-1-ylidene}-6-oxocyclohexa-1,3-dien-1-yl)benzoic acid EltroMbopag (SB-497115-GR) (Z)-3'-(2-(1-(3,4-DiMethylphenyl)-3-Methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid (Z)-3'-(2-(1-(3,4-Dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy- [1,1'-Biphenyl]-3-carboxylic acid, 3'-[2-[(2Z)-1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy- 3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid Eltrombopag Eltrombopag 3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid Eltrombopag Acid