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| CAS番号. | 202475-60-3 |
| 化学名: | |
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| 英語化学名: | JAK3 INHIBITOR I |
| 英語别名: | Janex 1;WHI-P131;JAK3 INHIBITOR I;A JAK3 inhibitor
WHI-P131;4-(6,7-dimethoxyquinazolin-4-ylamino)phenol;4-(4'-HYDROXYPHENYL)AMINO-6,7-DIMETHOXYQUINAZOLINE |
| CBNumber: | CB7130537 |
| 分子式: | C16H15N3O3 |
| 分子量: | 297.31 |
| MOL File: | 202475-60-3.mol |
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| JAK3 INHIBITOR I 物理性質 |
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| solubility : |
DMSO: 18 mg/mL, soluble
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JAK3 INHIBITOR I 化学特性,用途語,生産方法 |
使用
Janex 1 is a Janus tyrosine kinase 3 (JAK3) inhibitor. Inhibition of JAK3 has been shown to exhibit protective action against the development of T1D in non-obese diabetic (NOD) mice. Janex 1 has been shown to suppresses proliferation of short-term cultured NOD CD4+ T cells through induction of apoptosis, while promoting survival of a particular population of long-term cultured cells. It ameliorates the expression of TNF-α-induced cell adhesion molecules and improves myocardial vascular permeability. |
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| JAK3 INHIBITOR I 上流と下流の製品情報 |
原材料
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準備製品
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| JAK3 INHIBITOR I 生産企業 Global( 24)Suppliers |
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