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CAS番号. | 83027-13-8 |
化学名: | |
别名: | |
英語化学名: | AMN082 DIHYDROCHLORIDE |
英語别名: | AMN 082;AMN082 DIHYDROCHLORIDE;N,N'-bis(diphenylMethyl)ethylenediaMine;N,N'-DIBENZHYDRYLETHANE-1,2-DIAMINE DIHYDROCHLORIDE;N,N'-Bis(diphenylmethyl)-1,2-ethandiamine dihydrochloride;N,N'-BIS(DIPHENYLMETHYL)-1,2-ETHANEDIAMINE DIHYDROCHLORIDE |
CBNumber: | CB6849458 |
分子式: | C28H30Cl2N2 |
分子量: | 465.4572 |
MOL File: | 83027-13-8.mol |
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AMN082 DIHYDROCHLORIDE 物理性質 |
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AMN082 DIHYDROCHLORIDE 化学特性,用途語,生産方法 |
生物活性
The first selective mGlu 7 agonist. Potently inhibits cAMP accumulation and stimulates GTP γ S binding in recombinant cells and on membranes expressing mGlu 7 (EC 50 = 64-290 nM). Selective over other mGluR subtypes and selected ionotropic glutamate receptors up to 10 μ M. Acts via a novel allosteric site and is orally active and brain penetrant. Reduces haloperidol-induced catalepsy in rats. |
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AMN082 DIHYDROCHLORIDE 上流と下流の製品情報 |
原材料
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準備製品
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AMN082 DIHYDROCHLORIDE 生産企業 Global( 12)Suppliers |
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83027-13-8(AMN082 DIHYDROCHLORIDE) キーワード: |
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83027-13-8
N,N'-DIBENZHYDRYLETHANE-1,2-DIAMINE DIHYDROCHLORIDE
N,N'-BIS(DIPHENYLMETHYL)-1,2-ETHANEDIAMINE DIHYDROCHLORIDE
AMN082 DIHYDROCHLORIDE
AMN 082
N,N'-Bis(diphenylmethyl)-1,2-ethandiamine dihydrochloride
N,N'-bis(diphenylMethyl)ethylenediaMine
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