3-MATIDA 化学特性,用途語,生産方法 |
生物活性
Potent metabotropic glutamate mGlu 1 receptor antagonist (IC 50 = 6.3 μ M at rat mGlu 1a ). Displays ≥ 40-fold selectivity over other receptors: mGlu 5 , mGlu 2 , mGlu 4a (IC 50 > 300 μ M), NMDA and AMPA (IC 50 = 250 μ M). Neuroprotective in cultured murine cortical cells and rat hippocampal slice cultures in vitro . Reduces the volume of ischemia-induced brain infarcts in rats following systemic administration in vivo . |
|
|
| 3-MATIDA 上流と下流の製品情報 |
原材料
|
準備製品
|
| 3-MATIDA 生産企業 Global( 5)Suppliers |
|
|
|