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GW9662

CAS番号.22978-25-2
化学名:
别名:
英語化学名:GW9662
英語别名:GW9662;TIMTEC-BB SBB006523;2-CHLORO-5-NITROBENZANILIDE;2-CHLORO-5-NITRO-N-PHENYLBENZAMIDE;BenzaMide,2-chloro-5-nitro-N-phenyl-;2-Chloro-5-nitro-N-4-phenylbenzamide;N-[(2-chloro-5-nitrophenyl)-phenylmethylidene]hydroxylamine
CBNumber:CB3431922
分子式:C13H9ClN2O3
分子量:276.68
MOL File:22978-25-2.mol
GW9662 物理性質
融点 : 171-175 °C(lit.)
貯蔵温度 : 2-8°C
solubility : DMSO: 26 mg/mL, soluble
外見 : solid
color : white
CAS データベース: 22978-25-2(CAS DataBase Reference)
安全性情報
主な危険性 : Xi
Rフレーズ : 36-43
Sフレーズ : 26-36/37-24/25-22
WGK Germany : 3

GW9662 化学特性,用途語,生産方法

化学的特性
Off-White Solid
使用
A cell-permeable, selective and irreversible PPAR antagonist (IC50 = 3.3 nM, 32 nM, and 2 for PPAR, PPARa, and PPARd, respectively). Reported to covalently modify a cysteine residue in the binding site of PPAR. At a concentration of 10 , also
生物活性
Selective PPAR γ antagonist (IC 50 values are 3.3, 32 and 2000 nM for PPAR γ , PPAR α and PPAR δ respectively). Blocks the inhibition of osteoclast formation induced by IL-4 in the low micromolar range (1-2 μ M), therefore is more potent than BADGE (2,2-Bis[4-(2,3-epoxypropoxy)phenyl]propane ). Anticancer, inhibits growth of human mammary tumor cell lines.
GW9662 上流と下流の製品情報
原材料
準備製品
GW9662 生産企業      Global( 49)Suppliers     
名前電話番号ファックス番号電子メール国籍製品カタログ優位度
Shanghai Boyle Chemical Co., Ltd. Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)86-21-57758967sales@boylechem.comCHINA 5604 55
J & K SCIENTIFIC LTD. ----jkinfo@jkchemical.com;market3@jkchemical.comCHINA 96847 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:1893055203786-21-5032810967055399@qq.comCHINA 15983 69
Energy Chemical 021-58432009 / 400-005-6266021-58436166-800info@energy-chemical.comCHINA 44198 61
VDM Biochemicals 0330-25281810330-2528171sales@vdmbio.comUSA 511 64
Nanjing Chemlin Chemical Co., Ltd 025-83697070; 010-68547217+86-25-83453306sales@chemlin.com.cnCHINA 20120 64
Shanghai Hanhong Chemical Co., Ltd. 021-61521197,021-60496702,021-54302127,021-54306202,021-61525701,021-54308259+86-21-54291107jerry.ma@hanhonggroup.comCHINA 28730 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.comCHINA 32553 50
ShangHai Biochempartner Co.,Ltd +86 13818785766，400-021-9906 gaoqing@biochempartner.comCHINA 1167 62
BOC Sciences 1-631-504-60931-631-614-7828sales@bocsci.comUSA 9972 65
 
22978-25-2(GW9662) キーワード:
メトホルミン·塩酸塩
22978-25-2 2-CHLORO-5-NITRO-N-PHENYLBENZAMIDE 2-CHLORO-5-NITROBENZANILIDE GW9662 TIMTEC-BB SBB006523 2-Chloro-5-nitro-N-4-phenylbenzamide BenzaMide,2-chloro-5-nitro-N-phenyl- N-[(2-chloro-5-nitrophenyl)-phenylmethylidene]hydroxylamine
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