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| CAS番号. | 755037-03-7 |
| 化学名: | |
| 别名: | |
| 英語化学名: | Regorafenib |
| 英語别名: | Regafenib;regorafinib;BAY 73-4506;Regorafenib;Reggae sorafenib;Fluoro-Sorafenib;Regorafenib C3X-1410;Stivarga(regorafenib);BAY 73-4506(Regorafenib);Regorafenib (BAY 73-4506) |
| CBNumber: | CB32498792 |
| 分子式: | C21H15ClF4N4O3 |
| 分子量: | 482.8154128 |
| MOL File: | 755037-03-7.mol |
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Regorafenib 化学特性,用途語,生産方法 |
使用
It inhibits PDGFR tyrosine kinase with IC50=83nM. It is useful for the treatment of inflammation and as an anti-proliferative agent. |
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使用
BAY 73-4506 (Regorafenib) is a multikinase inhibitor with IC50 of 17, 40 and 69 nM c-KIT, VEGFR2, B-Raf. |
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使用
Regorafenib (BAY 73-4506) is a multi-target inhibitor for VEGFR1, VEGFR2, VEGFR3, PDGFRβ, Kit, RET and Raf-1 with IC50 of 13 nM/4.2 nM/46 nM, 22 nM, 7 nM, 1.5 nM and 2.5 nM, respectively |
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| Regorafenib 上流と下流の製品情報 |
原材料
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準備製品
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| Regorafenib 生産企業 Global( 118)Suppliers |
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