(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine

CAS番号.	767340-03-4
化学名:
别名:
英語化学名:	(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine
英語别名:	Sitagliptin EnaMine IMpurity;(2Z)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a];(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo-[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-t;3-AMino-1-(3-trifluoroMethyl-5,6-dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)-4-(2,4,5-trifluoro-phenyl)-but-2-en-1-one;(2Z)-3-aMino-1-[3-(trifluoroMethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)but-2-en-1-one;(2Z)-3-Amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one;(2Z)-3-Amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one;(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine;(Z)-3-aMino-1-(3-(trifluoroMethyl) -5,6-dihydro-[1,2,4]triazolo[4,3-a] pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one;(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine
CBNumber:	CB31564663
分子式:	C16H13F6N5O
分子量:	405.3
MOL File:	767340-03-4.mol

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine 物理性質

融点 :

178-180°C

貯蔵温度 :

Refrigerator

CAS データベース:

767340-03-4(CAS DataBase Reference)

安全性情報

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine 化学特性,用途語,生産方法

化学的特性
White Solid

使用
Sitagliptin intermediate. A dipeptidyl peptidase-4 inhibitor and an anti-hypertensive agent for the treatment of diabetes and hypertension.

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine 上流と下流の製品情報

原材料

準備製品

(2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine 生産企業 Global( 41)Suppliers

名前	電話番号	ファックス番号	電子メール	国籍	製品カタログ	優位度
J & K SCIENTIFIC LTD.	--	--	jkinfo@jkchemical.com;market3@jkchemical.com	CHINA	96847	76
BePharm Ltd. (Click here for a quote)	40068-59117; 86-21-51816456-8021/8022/8023	+86-21-51816740 (China Mainland); +86-21-51816457 (Others)	product@bepharm.com	CHINA	24999	61
Pure Chemistry Scientific Inc.	001-857-928-2050 or 1-888-588-9418	001-617-206-9595	sales@chemreagents.com	USA	9949	62
Chemfun Medical Technology(Shanghai) Co., Ltd.	021-67220633 & 021-37212706	+86-21-67220638	chemfun@chemfun.net	CHINA	21915	59
Shanghai Longsheng chemical Co.,Ltd.	0086-21-58099637,58099652,58099650,58099609 To 8017,8068; 13585536065	0086-21-33191781	sales@shlschem.com; bin.wu@shlschem.com；xianjun.hong@shlschem.com	CHINA	9850	59
Nanjing Chemlin Chemical Co., Ltd	025-83697070; 010-68547217	+86-25-83453306	sales@chemlin.com.cn	CHINA	20120	64
Chemsky（shanghai）International Co.,Ltd.	021-50135380		shchemsky@sina.com	CHINA	32553	50
XiaoGan ShenYuan ChemPharm co,ltd	Tell:86-712-2580635 Mobile:15527768850、 18986454762	86-712-2580625 QQ:1623551145	sales02@farchem.com	CHINA	9844	52
Wuhan Luohua Medical Technology Co.,Ltd.	13477084141 15327258908	+86(27)65566697	sales@luohuapharm.com	CHINA	495	60
China Langchem Inc.	0086-21-58956006,021-58950017;021-38701807	0086-21-58956100	sales@langchem.com	CHINA	11187	57

767340-03-4((2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine) キーワード:

1-(4-アミノ-6,7-ジメトキシキナゾリン-2-イル)-4-[[(テトラヒドロフラン)-2-イル]カルボニル]ピペラジン 2,6-ジメチル-7-オクテン-2-オールアルフゾシン·塩酸塩グリシン [電気泳動用] (2S,3E)-2-アミノ-4-(2-アミノエトキシ)-3-ブテン酸·塩酸塩 1-(4-アミノ-6,7-ジメトキシ-2-キナゾリニル)-4-[[(2,3-ジヒドロ-1,4-ベンゾジオキシン)-2-イル]カルボニル]ピペラジン·メタンスルホン酸 N-[3-[(4-アミノ-6,7-ジメトキシキナゾリン-2-イル)(メチル)アミノ]プロピル]テトラヒドロ-2-フランカルボアミド 2-[4-(2-フラニルカルボニル)ピペラジノ]-6,7-ジメトキシキナゾリン-4-アミン 6,7-ジメトキシ-2-[4-[(2,3-ジヒドロ-1,4-ベンゾジオキシン-2-イル)カルボニル]-1-ピペラジニル]キナゾリン-4-アミンピラジン

767340-03-4 （2Z）-2-amine -4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro][1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl] -1-(2,4,5-trifluorophenyl)but-2-en (2-4) (2Z)-3-Amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-α]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-α]pyrazin -7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine (2Z)-4-oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo[4,3-a] (2Z)-3-Amino-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-trifluorophenyl)but-2-en-2-amine 3-AMino-1-(3-trifluoroMethyl-5,6-dihydro-8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl)-4-(2,4,5-trifluoro-phenyl)-but-2-en-1-one (2Z)-3-aMino-1-[3-(trifluoroMethyl)-5H,6H,7H,8H-[1,2,4]triazolo[4,3-a]pyrazin-7-yl]-4-(2,4,5-trifluorophenyl)but-2-en-1-one (Z)-3-aMino-1-(3-(trifluoroMethyl) -5,6-dihydro-[1,2,4]triazolo[4,3-a] pyrazin-7(8H)-yl)-4-(2,4,5-trifluorophenyl)but-2-en-1-one Sitagliptin EnaMine IMpurity (2Z)-4-Oxo-4-[3-(trifluoromethyl)-5,6-dihydro[1,2,4]triazolo-[4,3-a]pyrazine-7(8H)-yl]-1-(2,4,5-t