ABT 263

CAS番号.	923564-51-6
化学名:
别名:
英語化学名:	ABT 263
英語别名:	ABT 263;Navitoclax;ABT-263,Navitoclax;Navitoclax (ABT-263);BenzaMide, 4-(4-((2-(4-chlorophenyl)-5,5-diMe;4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide;(S)-4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((4-morpholino-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamide;Benzamide, 4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl)methyl)-1-piperazinyl)-N-((4-(((1R)-3-(4-morpholinyl)-1-((phenylthio)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)-;ABT 263 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide;4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide ABT-26
CBNumber:	CB21872884
分子式:	C47H55ClF3N5O6S3
分子量:	974.61
MOL File:	923564-51-6.mol

ABT 263 物理性質

融点 :

114-116°C

貯蔵温度 :

-20°C Freezer, Under Inert Atmosphere

安全性情報

ABT 263 化学特性,用途語,生産方法

化学的特性
Pale Yellow Solid

使用
ABT-263 (Navitoclax) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤ 1 nM, respectively.

使用
A novel inhibitor of antiapoptotic BCL-2 proteins; a new promising anticancer drug candidate.

ABT 263 上流と下流の製品情報

原材料

準備製品

ABT 263 生産企業 Global( 55)Suppliers

名前	電話番号	ファックス番号	電子メール	国籍	製品カタログ	優位度
Zhengzhou HSH Science & Technology Co., Ltd.	18937192232;0371-55932928	0086-0371-55932928	1282296214@qq.com	CHINA	453	55
Lanzhou HuaHao Pharmaceutical Co., Ltd.	18189674620 13893303712	0931-7843863	18189674620@163.com	CHINA	462	55
Shanghai Boyle Chemical Co., Ltd.	Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)	86-21-57758967	sales@boylechem.com	CHINA	5604	55
J & K SCIENTIFIC LTD.	--	--	jkinfo@jkchemical.com;market3@jkchemical.com	CHINA	96847	76
Chembest Research Laboratories Limited	+86(0)21-20908456	+86(0)21-58180499	sales@biochembest.com	CHINA	6000	61
Capot Chemical Co., Ltd	+86 (0) 571 85 58 67 18	0086-571-85864795	sales@capotchem.com	CHINA	18282	66
JinYan Chemicals(ShangHai) Co.,Ltd.	13817811078,021-50426030	86-021-50426522,50426273	sales@jingyan-chemical.com	CHINA	10108	60
Chemsky（shanghai）International Co.,Ltd.	021-50135380		shchemsky@sina.com	CHINA	32553	50
Jinan Trio PharmaTech Co., Ltd.	+86 (531) 88811793；+86 (531) 88811783;+(0)18854807083;	+86 (531) 55696010 QQ981200479	sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market)	CHINA	1779	62
ShangHai Biochempartner Co.,Ltd	+86 13818785766，400-021-9906		gaoqing@biochempartner.com	CHINA	1167	62

923564-51-6(ABT 263) キーワード:

MG-132

923564-51-6 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide ABT 263 Benzamide, 4-(4-((2-(4-chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl)methyl)-1-piperazinyl)-N-((4-(((1R)-3-(4-morpholinyl)-1-((phenylthio)methyl)propyl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)- ABT-263,Navitoclax Navitoclax BenzaMide, 4-(4-((2-(4-chlorophenyl)-5,5-diMe Navitoclax (ABT-263) (S)-4-(4-((4'-chloro-4,4-dimethyl-3,4,5,6-tetrahydro-[1,1'-biphenyl]-2-yl)methyl)piperazin-1-yl)-N-((4-((4-morpholino-1-(phenylthio)butan-2-yl)amino)-3-((trifluoromethyl)sulfonyl)phenyl)sulfonyl)benzamide 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide ABT-26 ABT 263 4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide