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AM 251

CAS番号.183232-66-8
化学名:
别名:
英語化学名:AM 251
英語别名:AM 251;AM-251 ,99%;AM 251 (pharmaceutical);1-(2,4-DICHLOROPHENYL)-5-(4-IODOPHENYL)-4-METHYL-N-1-PIPERIDINYL-1 H-PYRAZOLE-3-CARBOXAMIDE;1H-Pyrazole-3-carboxamide, 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-;N-(PIPERIDIN-1-YL)-5-(4-IODOPHENYL)-1-(2,4-DICHLOROPHENYL)-4-METHYL-1H-PYRAZOLE-3-CARBOXAMIDE;1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide AM251
CBNumber:CB2169367
分子式:C22H21Cl2IN4O
分子量:555.24
MOL File:183232-66-8.mol
AM 251 物理性質
融点 : 195-196℃
貯蔵温度 : Store at RT
solubility : DMSO: >10 mg/mL, soluble
外見 : solid
color : white
安全性情報
主な危険性 : Xi
Rフレーズ : 36/37/38
Sフレーズ : 26-36
WGK Germany : 3

AM 251 化学特性,用途語,生産方法

化学的特性
White to Off-White Solid
使用
Inhibitor of CB1 receptors. AM 251is a biarylpyrazole compound which has been considered for many years as the prototypical cannabinoid (CB) receptor antagonist
生物活性
Potent CB 1 receptor antagonist (IC 50 = 8 nM, K i = 7.49 nM) that displays 306-fold selectivity over CB 2 receptors. Also potent GPR55 agonist (EC 50 = 39 nM). Also available as part of the Cannabinoid CB 1 Receptor Tocriset™ .
AM 251 上流と下流の製品情報
原材料
準備製品
AM 251 生産企業      Global( 37)Suppliers     
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J & K SCIENTIFIC LTD. ----jkinfo@jkchemical.com;market3@jkchemical.comCHINA 96847 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:1893055203786-21-5032810967055399@qq.comCHINA 15983 69
Ascent Scientific 44011798299884402030 700 369customerservice@ascentscientific.co.ukUNITED KINGDOM 282 60
VDM Biochemicals 0330-25281810330-2528171sales@vdmbio.comUSA 511 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.comCHINA 32553 50
T&W GROUP +86-21-61551611, 61551413, 61551420, 61551610+86-21-50676805contact@trustwe.comCHINA 13395 58
Shanghai Haoyuan Chemexpress Co., Ltd 86-21-5899859086-21-53700326, 86-21-58998590sales@chemexpress.cnCHINA 10011 61
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MedChemexpress LLC 609-228-6898609-228-5909sales@medchemexpress.cnUSA 4935 58
AdooQ BioScience, LLC +1 (866) 930-6790+1 (866) 333-9607info@adooq.comUSA 2786 58
 
183232-66-8(AM 251) キーワード:
183232-66-8 AM 251 1-(2,4-DICHLOROPHENYL)-5-(4-IODOPHENYL)-4-METHYL-N-1-PIPERIDINYL-1 H-PYRAZOLE-3-CARBOXAMIDE N-(PIPERIDIN-1-YL)-5-(4-IODOPHENYL)-1-(2,4-DICHLOROPHENYL)-4-METHYL-1H-PYRAZOLE-3-CARBOXAMIDE AM-251 ,99% AM 251 (pharmaceutical) 1H-Pyrazole-3-carboxamide, 1-(2,4-dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl- 1-(2,4-Dichlorophenyl)-5-(4-iodophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide AM251
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