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3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine

CAS番号.877399-52-5
化学名:
别名:
英語化学名:3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine
英語别名:Xalkori;PF 2341066;Crizotinib;Crozotinib;PF-02341066;PF-2341066/Crizotinib;Crizotinib,PF-02341066;Crizotinib (PF2341066);PF-02341066 Crizotinib;k-ras(g12c) inhibitor 6 NA Crizotinib
CBNumber:CB12473904
分子式:C21H22Cl2FN5O
分子量:450.343
MOL File:877399-52-5.mol
3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine 物理性質
安全性情報
国連危険物分類 : IRRITANT

3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine 化学特性,用途語,生産方法

化学的特性
White Solid
使用
A potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK). A potential antitumor agent.
使用
Crizotinib is a potent and selective dual inhibitor of mesenchymal-epithelial transition factor (c-MET) kinase and anaplastic lymphoma kinase (ALK). Crizotinib is a potential antitumor agent.
使用
PF-2341066 (Crizotinib) is a potent inhibitor of c-Met and ALK with IC50 of 11 nM and 24 nM, respectivley
3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine 上流と下流の製品情報
原材料
準備製品
3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine 生産企業      Global( 151)Suppliers     
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Jinan Trio PharmaTech Co., Ltd. +86 (531) 88811793；+86 (531) 88811783;+(0)18854807083;+86 (531) 55696010 QQ981200479sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market)CHINA 1779 62
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Shanghai Boyle Chemical Co., Ltd. Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)86-21-57758967sales@boylechem.comCHINA 5604 55
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877399-52-5(3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine) キーワード:
877399-52-5 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]-2-Pyridinamine (R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]pyridin-2-amine Crizotinib PF 2341066 PF-02341066 PF-2341066/Crizotinib 3-[1-(2,6-Dichloro-3-fluoro-phenyl)-ethoxy]-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine 3-[(1R)-1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]-2-aMinopyridine Crizotinib,PF-02341066 Xalkori (R)-3-[1-(2,6-Dichloro-3-fluorophenyl)ethoxy]-5-(1-piperidin-4-yl-1H- pyrazol-4-yl)pyridin-2-ylaMine [3-[[(R)-1-(2,6-Dichloro-3- fluorophenyl)ethyl]oxy]-5-[1-(piperidin-4-yl)-1H-pyrazol-4-yl]pyridin-2-yl]aMine 2-PyridinaMine, 3-[(1R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy]-5-[1-(4-piperidinyl)-1H-pyrazol-4-yl]- Crozotinib Crizotinib (PF2341066) PF-02341066 Crizotinib 3-((R)-1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1-(piperidin-4-yl)-1H-pyrazol-4-yl)pyridin-2-amine k-ras(g12c) inhibitor 6 NA Crizotinib
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