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| CAS番号. | 110078-46-1 |
| 化学名: | |
| 别名: | |
| 英語化学名: | PLERIXAFOR |
| 英語别名: | Mozobil;PLERIXAFOR;Sdz sid 791;Unii-S915p5499n;Plerixafor(AMD3100);AMD3100 (Plerixafor);Plerixafor/JM3100/AMD3100;1,4-bis((1,4,8,11-tetraazacyclotetradecan-1-yl)Methyl)benzene;1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)Methyl)benzene,95+%;1,1'-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane |
| CBNumber: | CB11011749 |
| 分子式: | C28H54N8 |
| 分子量: | 502.791 |
| MOL File: | 110078-46-1.mol |
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PLERIXAFOR 化学特性,用途語,生産方法 |
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使用
Plerixafor is a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM, respectively |
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使用
Plerixafor is a hematopoietic stem cell (HSC) mobilizer that inhibits the CXCR4 chemokine receptor and blocks binding of its ligand, stromal cell-derived factor-1-α (SDF-1-α).
on Dec. 15, 2008, as treatment in combination with granulocyte-colony stimulating factor (G-CSF) to mobilize HSCs to the peripheral blood for collection and subsequent autologous transplantation in p
atients with non-Hodgkin's lymphoma (NHL) and multiple myeloma (MM). |
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| PLERIXAFOR 上流と下流の製品情報 |
原材料
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準備製品
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| PLERIXAFOR 生産企業 Global( 63)Suppliers |
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110078-46-1
PLERIXAFOR
1,1'-[1,4-Phenylenebis(methylene)]bis-1,4,8,11-tetraazacyclotetradecane
1,4,8,11-Tetraazacyclotetradecane, 1,1'-(1,4-phenylenebis(methylene))bis-
Mozobil
Sdz sid 791
Unii-S915p5499n
1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylmethyl)phenyl]methyl]-1,4,8,11-tetrazacyclotetradecane
Plerixafor(AMD3100)
1-{[4-(1,4,8,11-tetraazacyclotetradecan-1-ylMethyl)phenyl]Methyl}-1,4,8,11-tetraazacyclotetradecane
plerixafor, AMD 3100, AMD-3100, AMD3100, JLK 169, Mozobil, 1-[[4-(1,4,8,11-tetrazacyclotetradec-1-ylMethyl)phenyl] Methyl]-1,4,8,11-tetrazacyclotetradecane
Plerixafor/JM3100/AMD3100
1,4-bis((1,4,8,11-tetraazacyclotetradecan-1-yl)Methyl)benzene
1,4-Bis((1,4,8,11-tetraazacyclotetradecan-1-yl)Methyl)benzene,95+%
AMD3100 (Plerixafor)
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