LY2228820

CAS No.	862507-23-1
Chemical Name:	LY2228820
Synonyms:	LY2228820;LY2228820 2MsOH;LY2228820 diMesylate;LY2228820(LY-2228820);5-(2-tert-butyl-4-(4-fluorophenyl)-1H-imidazol-5-yl)-3-neopentyl-3H-imidazo[4,5-b]pyridin-2-amine dimethanesulfonate;5-[2-(tert-Butyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-3-(2,2-dimethylpropyl)-3H-imidazo[4,5-b]pyridin-2-amine methanesulfonate;5-[2-(1,1-DiMethylethyl)-5-(4-fluorophenyl)-1H-iMidazol-4-yl]-3-(2,2-diMethylpropyl)-3H-iMidazo[4,5-b]pyridin-2-aMine DiMethanesulfonate
CBNumber:	CB82518277
Molecular Formula:	C26H37FN6O6S2
Formula Weight:	612.7369832
MOL File:	862507-23-1.mol

LY2228820 Property

Safety

LY2228820 Chemical Properties,Usage,Production

Usage
LY2228820 is a novel and potent p38MAPK inhibitor with potent antiinflammatory activity. LY2228820 significantly inhibited phosphorylation of MAPKAPK2 and/or HSP27, down stream targets of p38MAPK, in both multiple myeloma (MM) cell lines and LT-BMSCs. LY2228820 is a potential candidate to improve MM patient outcome both by enhancing the effect of Bortezomib (B675700) and by reducing osteoskeletal events.

LY2228820 Preparation Products And Raw materials

Raw materials

Preparation Products

LY2228820 Suppliers Global( 21)Suppliers

Supplier	Tel	Fax	Email	Country	ProdList	Advantage
Shanghai Boyle Chemical Co., Ltd.	Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)	86-21-57758967	sales@boylechem.com	CHINA	5604	55
J & K SCIENTIFIC LTD.	--	--	jkinfo@jkchemical.com;market3@jkchemical.com	CHINA	96847	76
Chembest Research Laboratories Limited	+86(0)21-20908456	+86(0)21-58180499	sales@biochembest.com	CHINA	6000	61
Chemsky (shanghai) International Co.,Ltd	021-50135380		shchemsky@sina.com	CHINA	15730	60
Jinan Trio PharmaTech Co., Ltd.	+86 (531) 88811793；+86 (531) 88811783;+(0)18854807083;	+86 (531) 55696010 QQ981200479	sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market)	CHINA	1779	62
ShangHai Biochempartner Co.,Ltd	+86 13818785766，400-021-9906		gaoqing@biochempartner.com	CHINA	1167	62
NCE Biomedical Co.,Ltd.	4000-027-021 \|24 hour enquiry :+86-13986109188 \|English:+86-15623472865 \|Japanese:+81-08033611988	+86-27-87599188	sales@ncebiomed.com	CHINA	1503	55
Shanghai Haoyuan Chemexpress Co., Ltd	86-21-58998590	86-21-53700326, 86-21-58998590	sales@chemexpress.cn	CHINA	10011	61
Shanghai Aladdin Bio-Chem Technology Co.,LTD	021-20337333/400-620-6333	021-50323701	sale@aladdin-e.com	CHINA	24330	65
MedChemexpress LLC	609-228-6898	609-228-5909	sales@medchemexpress.cn	USA	4935	58

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862507-23-1 LY2228820 5-[2-(1,1-DiMethylethyl)-5-(4-fluorophenyl)-1H-iMidazol-4-yl]-3-(2,2-diMethylpropyl)-3H-iMidazo[4,5-b]pyridin-2-aMine DiMethanesulfonate LY2228820(LY-2228820) LY2228820 2MsOH LY2228820 diMesylate 5-[2-(tert-Butyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-3-(2,2-dimethylpropyl)-3H-imidazo[4,5-b]pyridin-2-amine methanesulfonate C24H29FN62CH4O3S Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Protein Kinase Inhibitors and Activators 5-(2-tert-butyl-4-(4-fluorophenyl)-1H-imidazol-5-yl)-3-neopentyl-3H-imidazo[4,5-b]pyridin-2-amine dimethanesulfonate