CROMAKALIM

CAS No.	94470-67-4
Chemical Name:	CROMAKALIM
Synonyms:	BRL-34915;AKOS 91890;CROMAKALIM;(+/-)-CROMAKALIM;Cromakalim=([+/-]-trans-6-Cyano-3,4-dihydro-2,2-;rac-(3α,4β)-3-Hydroxy-2,2-dimethyl-4-(2-oxopyrrolidine-1-yl)chroman-6-carbonitrile;(-trans-6-Cyano-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-3,4-dihydro-2H-benzo[b]pyran-3-ol;[+/-]-TRANS-6-CYANO-3,4-DIHYDRO-2,2-DIMETHYL-4-[2-OXOPYRROLIDIN-1-YL]-2H-1-BENZOPYRAN-3-OL;(+/-)-TRANS-6-CYANO-3,4-DIHYDRO-2,2-DIMETHYL-4-(2-OXOPYRROLIDIN-1-YL)-2H-1-BENZOPYRAN-3-OL;TRANS-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-4-(2-OXO-1-PYRROLIDINYL)-2H-1-BENZOPYRAN-6-CARBONITRILE
CBNumber:	CB7771686
Molecular Formula:	C16H18N2O3
Formula Weight:	286.33
MOL File:	94470-67-4.mol

CROMAKALIM Property

mp :

242-244°C

storage temp. :

2-8°C

Safety

Safety Statements :

22-24/25

WGK Germany :

CROMAKALIM Chemical Properties,Usage,Production

Chemical Properties
White Crystalline Solid

Usage
Causes vasodilation by activation of potassim channels

Biological Activity
Prototypical K ATP channel opener. Relaxes rabbit isolated portal vein with an IC 50 value of 21 nM . Potent, orally active and hypotensive in vivo .

CROMAKALIM Preparation Products And Raw materials

Raw materials

Preparation Products

CROMAKALIM Suppliers Global( 16)Suppliers

Supplier	Tel	Fax	Email	Country	ProdList	Advantage
J & K SCIENTIFIC LTD.	--	--	jkinfo@jkchemical.com;market3@jkchemical.com	CHINA	96847	76
3B Pharmachem (Wuhan) International Co.,Ltd.	86-21-50328103 * 801、802、803、804 Mobile:18930552037	86-21-50328109	67055399@qq.com	CHINA	15983	69
Chemsky（shanghai）International Co.,Ltd.	021-50135380		shchemsky@sina.com	CHINA	32553	50
EMMX Biotechnology LLC	888-539-0666	888-539-0666	info@emmx.com	USA	8489	60

94470-67-4(CROMAKALIM)Related Search:

(S)-1-(2-Methoxyphenyl)ethylamine 3-CYANOBENZYLAMINE 1-(3-HYDROXYPROPYL)-2-PYRROLIDONE LEVCROMAKALIM 4-isopropoxybenzonitrile (R)-3-(1-aminoethyl)benzonitrile (S)-3-Amino-3-phenylpropan-1-ol 3-(4-methylphenoxy)propan-1-amine (S)-3-(1-Aminoethyl)benzonitrile 3-(methylaminomethyl)benzonitrile Benzenemethanamine, 2-(1-methylethoxy)- (9CI) 3-(1-PYRROLIDINYL)-1-BUTANOL 3-M-TOLYL-DL-BETA-ALANINOL 3-PYRROLIDINO-1,2-PROPANEDIOL CHEMBRDG-BB 5135828 N-(3-METHYLPHENYLMETHYL)BUTYLAMINE Anisonitrile 4-ETHOXYBENZONITRILE

BioChemical Cell Biology Cell Signaling and Neuroscience 94470-67-4 AKOS 91890 (+/-)-CROMAKALIM CROMAKALIM TRANS-3,4-DIHYDRO-3-HYDROXY-2,2-DIMETHYL-4-(2-OXO-1-PYRROLIDINYL)-2H-1-BENZOPYRAN-6-CARBONITRILE (+/-)-TRANS-6-CYANO-3,4-DIHYDRO-2,2-DIMETHYL-4-(2-OXOPYRROLIDIN-1-YL)-2H-1-BENZOPYRAN-3-OL [+/-]-TRANS-6-CYANO-3,4-DIHYDRO-2,2-DIMETHYL-4-[2-OXOPYRROLIDIN-1-YL]-2H-1-BENZOPYRAN-3-OL Monovalent Ion Channels Ion Channels Voltage-gated Ion Channels Potassium Channel Modulators Cromakalim=([+/-]-trans-6-Cyano-3,4-dihydro-2,2- All Inhibitors Inhibitors BRL-34915 rac-(3α*,4β*)-3,4-Dihydro-3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidine-1-yl)-2H-1-benzopyran-6-carbonitrile rac-(3α*,4β*)-3-Hydroxy-2,2-dimethyl-4-(2-oxopyrrolidine-1-yl)chroman-6-carbonitrile rac-3,4-Dihydro-3α*-hydroxy-2,2-dimethyl-4β*-(2-oxopyrrolidine-1-yl)-2H-1-benzopyran-6-carbonitrile (3R,4S)-rel-3,4-Dihydro-3-hydroxy-2,2-diMethyl-4-(2-oxo-1-pyrrolidinyl)-2H-1-benzopyran-6-carbonitrile (-trans-6-Cyano-2,2-dimethyl-4-(2-oxo-1-pyrrolidinyl)-3,4-dihydro-2H-benzo[b]pyran-3-ol