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CAS No. | 1162-65-8 |
Chemical Name: | AFLATOXIN B1 |
Synonyms: | AFBI;afb1;alflatoxin;NSC 529592;AFLATOXIN B;alflatoxinb1;AFLATOXIN B1;Aflaloxin B1;AFLATOXIN B1(RG);ahydro-4-methoxy- |
CBNumber: | CB5389650 |
Molecular Formula: | C17H12O6 |
Formula Weight: | 312.27 |
MOL File: | 1162-65-8.mol |
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AFLATOXIN B1 Property |
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Stability:: |
Stable. Incompatible with strong oxidizing agents. May be light or air sensitive. |
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AFLATOXIN B1 Chemical Properties,Usage,Production |
Chemical Properties
solid |
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Usage
Aflatoxins B1, B2, G1, G2 as secondary metabolites of fungal species such as Aspergillus flavus or Aspergillus parasiticus growing on a variety of foods (peanuts, nuts, spices, cereals). Aflatoxins a
re a group of very carcinogenic mycotoxins with hepatotoxic effects.
Aflatoxin is biotransformed to genotoxic intermediates by P450 Phase I enzymes, mainly CYP3A4 via aflatoxin B1 3-hydroxylation.
Detoxification depends on Phase II enzymes, such as Glutathione S-Transferase and AFB(1)-aldehyde reductase (AFAR). |
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Usage
Aflatoxin B1 is the major analogue of a family of bisfuranocoumarin mycotoxins produced by Aspergillus flavus and related species. Alfatoxin B1 exhibits a distinctive UV spectrum and blue fluorescence. Alfatoxins are among the most potent mycotoxins known but are in fact "pre-toxins", requiring metabolic activation to the toxic principle. Aflatoxins are found widely in nature in trace amounts, particularly in grains and nuts. The toxicity of these metabolites was first recognised in the 1950s and their structures elucidated in 1963. Aflatoxins have been extensively reviewed. |
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Usage
Aflatoxin B1 is the major analogue of a family of bisfuranocoumarin mycotoxins produced by Aspergillus flavus and related species. Aflatoxin B1 exhibits a distinctive UV spectrum and blue fluorescence. Aflatoxins are among the most potent mycotoxins known but are in fact "pre-toxins", requiring metabolic activation to the toxic principle. Aflatoxins are found widely in nature in trace amounts, particularly in grains and nuts. The toxicity of these metabolites was first recognised in the 1950s and their structures elucidated in 1963. Aflatoxins have been extensively reviewed. |
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General Description
Colorless to pale yellow crystals or white powder. Exhibits blue fluorescence. |
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Air & Water Reactions
Sensitive to exposure to air and light. Water insoluble. |
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Reactivity Profile
AFLATOXIN B1 is incompatible with strong oxidizing agents, strong acids and strong bases. |
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Fire Hazard
Flash point data for AFLATOXIN B1 are not available; however, AFLATOXIN B1 is probably combustible. |
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AFLATOXIN B1 Preparation Products And Raw materials |
Raw materials
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Preparation Products
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AFLATOXIN B1 Suppliers Global( 58)Suppliers |
Supplier | Tel | Fax | Email | Country | ProdList | Advantage |
Changsha Jing Kang New Material Technology Co., Ltd.
| 0731-82067109 18874718518 | 0731-85118349 | ma_haihong@sina.com | CHINA |
1597
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50
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Shanghai Baoman Biotechnology Co., Ltd.
| 021-62130998 | | baomanbio@163.com | CHINA |
5288
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55
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J & K SCIENTIFIC LTD.
| -- | -- | jkinfo@jkchemical.com;market3@jkchemical.com | CHINA |
96847
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76
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Meryer (Shanghai) Chemical Technology Co., Ltd.
| +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-59487313(Beijing) | +86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) | sh@meryer.com | CHINA |
40407
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62
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JinYan Chemicals(ShangHai) Co.,Ltd.
| 13817811078,021-50426030 | 86-021-50426522,50426273 | sales@jingyan-chemical.com | CHINA |
10108
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60
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Chemsky(shanghai)International Co.,Ltd.
| 021-50135380 | | shchemsky@sina.com | CHINA |
32553
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50
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BEST-REAGENT
| 028-85973071 028-85973075 | 028-85973075 | service@best-reagent.com | CHINA |
9961
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57
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Dalian Meilun Biotech Co., Ltd.
| 0411-66771943;0411-66771942 | 0411-66771945 | sales@meilune.com | CHINA |
5010
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58
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ShangHai YuanYe Biotechnology Co., Ltd.
| 021-61312847 qq:2797782341 | 021-60137357 | 2797782341@qq.com | CHINA |
7597
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60
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Chengdu Ai Keda Chemical Technology Co., Ltd.
| 4008-755-333 ; 028-86676798 ; 028-86757656 | 028-86757656 | aikeshiji@163.com | CHINA |
9909
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55
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(6ar-cis)-ahydro-4-methoxy
)(1)benzopyran-1,11-dione
1-Cyclopentene-1-carboxylic acid, 2-(3a,8a-dihydro-4-hydroxy-6-methoxyfuro[2,3-b]benzofuran-5-yl)-5-oxo-, delta-lactone
2,3,6aalpha,9aalpha-tetrahydro-4-methoxycyclopenta(c)furo(3’,2’:4,5)furo(2,3-h
4-Methoxy-2,3,6a,9a-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-H]chromene-1,11-dione
6-methoxydifurocoumarone
afb1
AFBI
AflatoxinB1(form1)
ahydro-4-methoxy-
alflatoxin
alflatoxinb1
alpha-tetrahydro-4-methoxy-
Cyclopenta(c)furo(3',2':4,5)furo(2,3-h)(1)benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy-
cyclopenta(c)furo(3’,2’:4,5)furo(2,3-h)(1)benzopyran-1,11-dione,2,3,6a,9a-tet
cyclopenta(c)furo(3’,2’:4,5)furo(2,3-h)(1)benzopyran-1,11-dione,2,3,6a,9a-tetr
cyclopenta(c)furo(3’,2’:4,5)furo(2,3-h)(1)benzopyran-1,11-dione,2,3,6aalpha,9a
Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6a,9a-tetrahydro-4-methoxy-, (6aR-cis)-
Cyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione, 2,3,6aalpha,9aalpha-tetrahydro-4-methoxy-
rahydro-4-methoxy-
BioChemical
1162-65-8
Carcinogens
Cancer Research
AFLATOXIN B
AFLATOXIN B1
AFLATOXIN B1, ASPERGILLUS FLAVUS
2,3,6aalpha,9aalpha-tetrahydro-4-methoxycyclopenta[c]furo[2',3':4,5]furo[2,3-h]chromene-1,11-dione
AFLATOXIN B1 FROM ASPERGILLUS FLAVUS
AFLATOXIN B(1) FROM ASPERGILLUS FLAVUS, VIAL WITH 10 MG
Aflatoxin B1, crystalline
C17H12O6
aflatoxin b1 solution
aflatoxin b1solution
AFLATOXIN B1(RG)
A
AA to ALBiotoxins
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Mycotoxins
Single component solutions
MoldCell Signaling Enzymes
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Xenobiotics and Drug Metabolism
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(6aR)-4-Methoxy-2,3,6aα,9aα-tetrahydrocyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione
2,3,6aα,9aα-Tetrahydro-4-methoxycyclopenta[c]furo[3',2':4,5]furo[2,3-h][1]benzopyran-1,11-dione
Chiral Reagents
Heterocycles
Intermediates & Fine Chemicals
Metabolites & Impurities
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