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| CAS No. | 950762-95-5 |
| Chemical Name: | PCI 34051 |
| Synonyms: | PCI-34051;PCI 34051;1-(4-methoxybenzyl)-N-hydroxy-1H-indole-6-carboxamide;N-hydroxy-1-(4-Methoxybenzyl)-1H-indole-6-carboxaMide;N-Hydroxy-1-[(4-methoxyphenyl)methyl]-1H-indole-6-carboxamide;1H-Indole-6-carboxamide, N-hydroxy-1-[(4-methoxyphenyl)methyl]- |
| CBNumber: | CB52622953 |
| Molecular Formula: | C17H16N2O3 |
| Formula Weight: | 296.32054 |
| MOL File: | 950762-95-5.mol |
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PCI 34051 Chemical Properties,Usage,Production |
Usage
PCI-34051 is a potent, histone deacetylase 8 (HDAC8)-specific inhibitor. PCI-34051 induces caspase-dependent apoptosis in cell lines derived from T-cell lymphomas or leukemias. PCI-34051 did not affect other hematopoietic or solid tumor lines. PCI-34051 treatment has been shown to significantly reduce cholesterol accumulation in Niemann-Pick type C1 gene mutated human fibroblast. |
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| PCI 34051 Preparation Products And Raw materials |
Raw materials
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Preparation Products
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| PCI 34051 Suppliers Global( 21)Suppliers |
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