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VERRUCULOGEN

CAS No.12771-72-1
Chemical Name:VERRUCULOGEN
Synonyms:tr1;T1R1;TRXR1;GPR70;TAS1R1;NA 209A;GRIM-12;MGC9145;TR-1TOXIN;VERRUCOLOGEN
CBNumber:CB0294003
Molecular Formula:C27H35N3O7
Formula Weight:513.58
MOL File:12771-72-1.mol
VERRUCULOGEN Property
storage temp. : 2-8°C
Safety
Hazard Codes : T,Xn,F
Risk Statements : 23/24/25-36-20/21/22-11
Safety Statements : 36/37/39-45-36/37-26-16
RIDADR : UN 2811 6.1/PG 2
WGK Germany : 3
RTECS : JH4920000

VERRUCULOGEN Chemical Properties,Usage,Production

Usage
Verruculogen is a tremorgenic mycotoxin, first isolated from Penicillium verruculosum in 1972. The structure was resolved as an indole alkaloid in 1974. Verruculogen is produced by several species of Penicillium and Aspergillus and its presence is a useful taxonomic phenotypic marker. The tremorgenic action of verruculogen is associated with increases in spontaneous glutamate and aspartate release, decreases in GABA levels and, at toxic doses, an increase in the number and decrease in the affinity of DHP receptors in rat cortex. In in vitro guinea pig ileum preparations, verruculogen causes an increase in contractile responses due to electrical field stimulation, attributed to enhancement of acetylcholine from presynaptic nerve terminals. Verruculogen also inhibits Ca2+-activated K+ channels, and is a cell cycle inhibitor blocking division at the M phase.
VERRUCULOGEN Preparation Products And Raw materials
Raw materials
Preparation Products
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12771-72-1(VERRUCULOGEN)Related Search:
N-(1-METHYL-3-PHENYLPROPYL)-N-VALERAMIDE N-PHENYL-3-PIPERIDINAMINE CHEMBRDG-BB 4013122 GLYCINE ANHYDRIDE N,N-Dipropylpropionamide (S)-3-METHYL-2-KETOPIPERAZINE CHEMBRDG-BB 4014926 6-METHOXY-2,3-DIHYDRO-1H-INDOLE N-acetyl-1,6-diaminohexane 4-Methyl-1-piperazineethanamine 3-AMINOPIPERIDINE 2-Aminoethyldiisopropylamine 1-dibutylaminopropan-2-ol 2-(4-METHYL-PIPERIDIN-1-YL)-ETHYLAMINE 2-Ethylpiperazine 2-PIPERIDYLMETHYLAMINE tert-Amyl hydroperoxide 1-Piperazineethanamine,N,4-dimethyl-(9CI)
12771-72-1 VERRUCULOGEN VERRUCULOGEN, PENICILLIUM VERRUCULOSUM 3h)-dione,1,10,10a,14,14a,15b-hexahydro-10,10a-dihydroxy-7-methoxy-2,2-dimeth 5h,12h-3,4-dioxa-5a,11a,15a-triazacyclooct(lm)indeno(5,6-b)fluorene-11,15(2h,1 tr1 verruculogentr1 yl-5-(2-methyl-1-propenyl)-,(5r-(5-alpha,10-alpha,10a-alpha,14a-alpha-15b-alp verruculogen from penicillium*verruculosum VERRUCULOGEN FROM PENICILLIUM VERRUCULOS C27H35N3O7 VERRUCOLOGEN TR-1TOXIN C27H33N3O7 (5R)-1,10,10a,14,14aα,15bα-Hexahydro-10α,10aα-dihydroxy-7-methoxy-2,2-dimethyl-5α-(2-methyl-1-propenyl)-12H-3,4-dioxa-5a,11a,15a-triazacyclooct[lm]indeno[5,6-b]fluorene-11,15(2H,13H)-dione (5R)-2,5,10,10a,11,12,13,14,14aα,15bα-Decahydro-10α,10aα-dihydroxy-7-methoxy-2,2-dimethyl-5α-(2-methyl-1-propenyl)-3,4-dioxa-5a,11a,15a-triaza-1H-cyclooct[lm]indeno[5,6-b]fluorene-11,15-dione (5R-(5alpha,10 alpha,10Aalpha,14aalpha,15balpha))-1,10,10A,14,14A,15B-hexahydro-10,10A-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-5H,12H-3,4-dioxa-5A,11A,15A-triaza cyclooct (1m) indeno (5,6-B)fluorene-11,15(2H,13H)-dione 5H,12H-3,4-Dioxa-5A,11A,15A-triazacyclooct(lm)indeno(5,6-B)fluorene-11,15(2H,13H)-dione, 1,10,10A,14,14A,15B-hexahydro-10,10A-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-, (5R,10S,10ar,14as,15bs)- 5H,12H-3,4-Dioxa-5A,11A,15A-triazacyclooct(lm)indeno(5,6-B)fluorene-11,15(2H,13H)-dione, 1,10,10A,14,14A,15B-hexahydro-10,10A-dihydroxy-7-methoxy-2,2-dimethyl-5-(2-methyl-1-propenyl)-,(5R-(5-alpha,10-alpha,10A-alpha,14A-alpha-15B-alpha))- Verruculogenresearch grade antibiotic NA 209A Verruculogen NA 209A TR 1 toxin Verruculogen solution GRIM-12 MGC9145 TRXR1 TXNRD1 human Anti-TAS1R1 (N-terminal) antibody produced in rabbit GPR70 T1R1 TAS1R1 ANTI-TAS1R1 (CENTER) antibody produced in rabbit Taste receptor type 1 member 1 Anti-TAS1R1 (C-terminal) antibody produced in rabbit
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