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| CAS-Nr. | 63208-82-2 |
| Bezeichnung: | |
| Englisch Name: | Pifithrin-α (PFTα) |
| Synonyma: |
(PFTαZinc03874684;PIFITHRIN-ALPHA;PFTα hydrobroMide;PFT-α,Pifithrin-α;Pifithrin-α (PFTα);Pifithrin-alpha . HBr;Pifithrin-Hydrobromide;PIFITHRIN-ALPHA HYDROBROMIDE;Pifithrin
Pifithrin-alpha |
| CBNumber: | CB9700743 |
| Summenformel: | C16H19BrN2OS |
| Molgewicht: | 367.3 |
| MOL-Datei: | 63208-82-2.mol |
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| Pifithrin-α (PFTα) physikalisch-chemischer Eigenschaften |
| Schmelzpunkt:: |
192.1-192.5 °C(lit.)
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| solubility : |
DMSO: 20 mg/mL
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Pifithrin-α (PFTα) Chemische Eigenschaften,Einsatz,Produktion Methoden |
Biologische Aktivit?t
Inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorders. Active in vivo ; protects mice from the side-effects of cancer therapy associated with p53 induction. Potentially increases reprogramming efficiency of human somatic cells to induced pluripotent stem cells (iPSCs) by silencing p53. Also aryl hydrocarbon receptor (AHR) agonist, causes upregulation of AHR target gene CYP1A1 (EC 50 = 1.1 μ M). |
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| Pifithrin-α (PFTα) Upstream-Materialien And Downstream Produkte |
Upstream-Materialien
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Downstream Produkte
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| Pifithrin-α (PFTα) Anbieter Lieferant Produzent Hersteller Vertrieb Händler. Global( 40)Lieferanten |
| Firmenname | Telefon | Fax | E-Mail | Land | Produktkatalog | Edge Rate |
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NCE Biomedical Co.,Ltd.
| 4000-027-021 |24 hour enquiry :+86-13986109188 |English:+86-15623472865 |Japanese:+81-08033611988 | +86-27-87599188 | sales@ncebiomed.com | CHINA |
1503
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55
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3B Pharmachem (Wuhan) International Co.,Ltd.
| 86-21-50328103 * 801、802、803、804 Mobile:18930552037 | 86-21-50328109 | 67055399@qq.com | CHINA |
15983
|
69
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Jinan Trio PharmaTech Co., Ltd.
| +86 (531) 88811793；+86 (531) 88811783;+(0)18854807083; | +86 (531) 55696010 QQ981200479 | sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market) | CHINA |
1779
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62
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ShangHai Biochempartner Co.,Ltd
| +86 13818785766，400-021-9906 | | gaoqing@biochempartner.com | CHINA |
1167
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62
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Syntechem Co.,Ltd
| info@syntechem.com QQ 421151915 | E-Mail Inquiry | info@syntechem.com | CHINA |
13109
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57
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Hangzhou Sage Chemical Co., Ltd.
| 0571-86818502 | Pls mail us for more information! | info@sagechem.com | CHINA |
10286
|
58
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Shanghai Haoyuan Chemexpress Co., Ltd
| 86-21-58998590 | 86-21-53700326, 86-21-58998590 | sales@chemexpress.cn | CHINA |
10011
|
61
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Shanghai Aladdin Bio-Chem Technology Co.,LTD
| 021-20337333/400-620-6333 | 021-50323701 | sale@aladdin-e.com | CHINA |
24330
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65
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MedChemexpress LLC
| 609-228-6898 | 609-228-5909 | sales@medchemexpress.cn | USA |
4935
|
58
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Shanghai Tauto Biotech Co., Ltd
| 0086-21-51320588 | 0086-21-51320502 | export2@tautobiotech.com | CHINA |
4011
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66
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PIFITHRIN-ALPHA
PIFITHRIN-ALPHA HYDROBROMIDE
63208-82-2
2-(2-IMINO-4,5,6,7-TETRAHYDROBENZOTHIAZOL-3-YL)-1-P-TOLYLETHANONE, HBR
1-(4-METHYLPHENYL)-2-(4,5,6,7-TETRAHYDRO-2-IMINO-3(2H)-BENZOTHIAZOLYL)ETHANONE HYDROBROMIDE
1-(4-METHYLPHENYL)-2-(4,5,6,7-TETRAHYDRO-2-IMINO-3(2H)-BENZOTHIAZOLYL)ETHANONE, MONOHYDROBROMIDE
Apoptosis Inhibitors
Apoptosis and Cell Cycle
Cell Biology
Cell Signaling and Neuroscience
BioChemical
Pifithrin-Hydrobromide
2-(2-imino-4,5,6,7-tetrahydrobenzothiazol-3-yl)-1-p-tolylethanone hydrobromide
Caspases/Apoptosis
PFT-α,Pifithrin-α
Zinc03874684
C16H18N2OSHBr
Ethanone, 1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-iMino-3(2H)-benzothiazolyl)-, MonohydrobroMide
PFTα hydrobroMide
2-(2-iMino-4,5,6,7-tetrahydrobenzo[d]thiazol-3(2H)-yl)-1-p-tolylethanone hydrobroMide
Pifithrin-α (PFTα)
Inhibitor
Pifithrin-alpha . HBr
Ethanone, 1-(4-methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)-, hydrobromide (1:1)
1-(4-Methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)ethanone hydrobromide Pifithrin-α
Pifithrin
Pifithrin-alpha
(PFT&alpha
|