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| CAS-Nr. | 162042-44-6 |
| Bezeichnung: | |
| Englisch Name: | L371,257 |
| Synonyma: |
L371,257;1-[4-[(1-Acetyl-4-piperidinyl)oxy]-2-methoxybenzoyl]-4-(2-oxo-2H-3,1-benzoxazin-1(4H)-yl)piperidine |
| CBNumber: | CB8850593 |
| Summenformel: | C28H33N3O6 |
| Molgewicht: | 507.584 |
| MOL-Datei: | 162042-44-6.mol |
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| L371,257 physikalisch-chemischer Eigenschaften |
| storage temp. : |
Store at RT |
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L371,257 Chemische Eigenschaften,Einsatz,Produktion Methoden |
Biologische Aktivit?t
Potent, high affinity human oxytocin (OT) receptor antagonist (K i = 4.6 nM) that displays > 800-fold selectivity over human arginine vasopressin receptors V 1a and V 2 . Antagonizes oxytocin-induced contractions in isolated rat uterine tissue (pA 2 = 8.44) and in anesthetised rats following intravenous and intraduodenal administration. Orally active. |
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| L371,257 Upstream-Materialien And Downstream Produkte |
Upstream-Materialien
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Downstream Produkte
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| L371,257 Anbieter Lieferant Produzent Hersteller Vertrieb Händler. Global( 4)Lieferanten |
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