|
|
| CAS-Nr. | 154447-35-5 |
| Bezeichnung: | |
| Englisch Name: | NU7026 |
| Synonyma: |
LY 293646;2-(4-Morpholinyl)-4H-naphtho[1,2-b]pyran-4-one;2-(4-Morpholinyl)-4H-naphthol[1,2-b]pyran-4-one;4H-Naphtho[1,2-b]pyran-4-one, 2-(4-morpholinyl)-;2-(4-Morpholinyl)-4H-naphtho[1,2-b]pyran-4-one NU7026 |
| CBNumber: | CB8503981 |
| Summenformel: | C17H15NO3 |
| Molgewicht: | 281.31 |
| MOL-Datei: | 154447-35-5.mol |
|
|
|
|
| NU7026 physikalisch-chemischer Eigenschaften |
|
|
|
|
| solubility : |
DMSO: 3 mg/mL at 60 °C, soluble
|
|
|
|
|
|
|
NU7026 Chemische Eigenschaften,Einsatz,Produktion Methoden |
Biologische Aktivit?t
ATP-competitive inhibitor of DNA-dependent protein kinase (DNA-PK). Displays selectivity over other PIKK family enzymes (IC 50 values are 0.23, 13.0, > 100 and > 100 μ M for DNA-PK, PI3K, ATM and ATR respectively). Radiosensitizes both proliferating and quiescent mouse embryonic fibroblast cells to IR and inhibits DSB repair. |
|
|
| NU7026 Upstream-Materialien And Downstream Produkte |
Upstream-Materialien
|
Downstream Produkte
|
| NU7026 Anbieter Lieferant Produzent Hersteller Vertrieb Händler. Global( 27)Lieferanten |
|
|
|
|
|