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(3S,6S,12aS)-1,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic acid 1,1-dimethylethyl ester Produkt Beschreibung

CAS-Nr.461054-93-3
Bezeichnung:
Englisch Name:(3S,6S,12aS)-1,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic acid 1,1-dimethylethyl ester
Synonyma:
Ko 143;12aS)-;4-dioxo-;Ko143 ,99%;6]pyrido[3;Pyrazino[1';Ko143 hydrate;4-b]indole-3-propanoicacid;12a-octahydro-9-Methoxy-6-(2-Methylpropyl)-1;tert-Butyl 3-((3S,6S,12aS)-6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7, 12,12a-octahydropyrazino[1
CBNumber:CB81562442
Summenformel:C26H35N3O5
Molgewicht:469.57
MOL-Datei:461054-93-3.mol
(3S,6S,12aS)-1,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic acid 1,1-dimethylethyl ester physikalisch-chemischer Eigenschaften
Schmelzpunkt:: 147 ºC
Dichte: 1.24
storage temp. : Desiccate at -20°C
Sicherheit
Kennzeichnung gefährlicher: Xi
R-Sätze:: 36/37/38
S-Sätze:: 26-36

(3S,6S,12aS)-1,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic acid 1,1-dimethylethyl ester Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden
A potent BCRP (breast cancer resistance protein) inhibitor
Biologische Aktivit?t
Potent and selective breast cancer resistance protein multidrug transporter (BCRP) inhibitor (EC 90 = 26 nM). Displays > 200-fold selectivity over P-gp and MRP-1 transporters. Increases intracellular drug accumulation and reverses BCRP-mediated multidrug resistance.
(3S,6S,12aS)-1,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic acid 1,1-dimethylethyl ester Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(3S,6S,12aS)-1,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic acid 1,1-dimethylethyl ester Anbieter Lieferant Produzent Hersteller Vertrieb Händler.      Global( 25)Lieferanten     
FirmennameTelefonFaxE-MailLandProduktkatalogEdge Rate
J & K SCIENTIFIC LTD. ----jkinfo@jkchemical.com;market3@jkchemical.comCHINA 96847 76
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:1893055203786-21-5032810967055399@qq.comCHINA 15983 69
Chembest Research Laboratories Limited +86(0)21-20908456+86(0)21-58180499sales@biochembest.comCHINA 6000 61
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418001-617-206-9595sales@chemreagents.comUSA 9949 62
Lanzhou Boc Chemical Co., Ltd 86-021-34975602/34975603 021-34970311+86-21-34975602-805sales@bocchem.comCHINA 949 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.comCHINA 298 58
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.comCHINA 15730 60
ShangHai Biochempartner Co.,Ltd +86 13818785766，400-021-9906 gaoqing@biochempartner.comCHINA 1167 62
Shanghai LiuShi Pharmaceutical Technology Co., Ltd. 021-60135539021-38721356shlschemical@hotmail.comCHINA 9967 55
Shanghai Haoyuan Chemexpress Co., Ltd 86-21-5899859086-21-53700326, 86-21-58998590sales@chemexpress.cnCHINA 10011 61
 
461054-93-3((3S,6S,12aS)-1,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic acid 1,1-dimethylethyl ester)Verwandte Suche:
3-(Indol-3-yl)propionsure Methoxy 4-Methoxy-anilin p-(Chlormethyl)anisol Anisaldehyd (Trifluormethoxy)benzol 4-Methoxyphenylaceton 4-Methoxyphenylessigsäure Anisol 3-(METHOXYMETHOXY)BENZALDEHYDE
461054-93-3 Pyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic acid, 1,2,3,4,6,7,12,12a-octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxo-, 1,1-dimethylethyl ester, (3S,6S,12aS)-(Ko143) Ko 143 (3S,6S,12aS)-1,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-(2-methylpropyl)-1,4-dioxopyrazino[1',2':1,6]pyrido[3,4-b]indole-3-propanoic acid 1,1-dimethylethyl ester C26H35N3O5 C26H36N3O5 Ko143 ,99% 12a-octahydro-9-Methoxy-6-(2-Methylpropyl)-1 12aS)- 4-b]indole-3-propanoicacid 4-dioxo- 6]pyrido[3 Pyrazino[1' Chiral Reagents Heterocycles Inhibitors Intermediates & Fine Chemicals Pharmaceuticals Ko143 hydrate tert-Butyl 3-((3S,6S,12aS)-6-isobutyl-9-methoxy-1,4-dioxo-1,2,3,4,6,7, 12,12a-octahydropyrazino[1 (3S,6S,12aS)-1,2,3,4,6,7,12,12a-Octahydro-9-methoxy-6-( 2-methylpropyl)-1,4-dioxopyrazino[1′,2′:1,6]pyrido[3,4- b]indole-3-propanoic acid 1,1-dimethylethyl ester hydrate
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