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| CAS-Nr. | 522629-08-9 |
| Bezeichnung: | |
| Englisch Name: | CGP 57380 |
| Synonyma: |
CGP 57380;MNK1 Inhibitor;N3-(4-Fluorophenyl)-1H-pyrazolo[3,4-d]pyrimidine-3,4-diamine;CGP57380, N3-(4-fluorophenyl)-1h-pyrazolo[3,4-d]pyrimidine-3,4-diamine |
| CBNumber: | CB6972321 |
| Summenformel: | C11H9FN6 |
| Molgewicht: | 244.232 |
| MOL-Datei: | 522629-08-9.mol |
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| CGP 57380 physikalisch-chemischer Eigenschaften |
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CGP 57380 Chemische Eigenschaften,Einsatz,Produktion Methoden |
Biologische Aktivit?t
Inhibitor of MAP-kinase interacting kinase-1 (Mnk1, MKNK1) (IC 50 = 2.2 μ M) that displays selectivity over p38, JNK1, ERK1, ERK2, PKC and c-src family kinases. Blocks phosphorylation of eIF4E in cellular assays (IC 50 = 3 μ M) and inhibits LPS-induced TNF α expression in macrophages. |
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| CGP 57380 Upstream-Materialien And Downstream Produkte |
Upstream-Materialien
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Downstream Produkte
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| CGP 57380 Anbieter Lieferant Produzent Hersteller Vertrieb Händler. Global( 13)Lieferanten |
| Firmenname | Telefon | Fax | E-Mail | Land | Produktkatalog | Edge Rate |
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3B Pharmachem (Wuhan) International Co.,Ltd.
| 86-21-50328103 * 801、802、803、804 Mobile:18930552037 | 86-21-50328109 | 67055399@qq.com | CHINA |
15983
|
69
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Shanghai Ennopharm Co., Ltd.
| +86 (21) 6435-5022 | | ennopharm@hotmail.com | CHINA |
4274
|
65
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Chengdu JuHui Chemical Technology Co., Ltd.
| 028-85062459 028-64353063 18782929954 QQ:401639705 | 028-85062459 | juhuichemical@163.com | CHINA |
1757
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55
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Shanghai Haoyuan Chemexpress Co., Ltd
| 86-21-58998590 | 86-21-53700326, 86-21-58998590 | sales@chemexpress.cn | CHINA |
10011
|
61
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MedChemexpress LLC
| 609-228-6898 | 609-228-5909 | sales@medchemexpress.cn | USA |
4935
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58
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AdooQ BioScience, LLC
| +1 (866) 930-6790 | +1 (866) 333-9607 | info@adooq.com | USA |
2786
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58
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AdooQ Bioscience CHINA
| 400-025-6535 | 025-68650336 | info@adooq.cn | CHINA |
2299
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60
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Hubei Jusheng Technology Co.,Ltd
| North:027-59599241,18871490274,QQ:1400878000 South:027-59531287,15727001360,QQ:1400878866 | ℡ 027-83861211 | 469501031@qq.com | CHINA |
10512
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58
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