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| CAS-Nr. | 220792-57-4 |
| Bezeichnung: | |
| Englisch Name: | AMINOPURVALANOL A |
| Synonyma: |
NG-97;AMINOPURVALANOL A;AMINOPURVALANOL A (APURV);(2R)-2-[[6-[(3-AMINO-5-CHLOROPHENYL)AMINO]-9-(1-METHYLETHYL)-9H-PURIN-2-YL]AMINO]-3-METHYL-1-BUTANOL |
| CBNumber: | CB4164371 |
| Summenformel: | C19H26ClN7O |
| Molgewicht: | 403.91 |
| MOL-Datei: | 220792-57-4.mol |
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| AMINOPURVALANOL A physikalisch-chemischer Eigenschaften |
| storage temp. : |
Store at +4°C |
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AMINOPURVALANOL A Chemische Eigenschaften,Einsatz,Produktion Methoden |
Biologische Aktivit?t
Cell-permeable cyclin-dependent kinase inhibitor. IC 50 values are 0.033, 0.033, 0.028 and 0.020 μ M for cdk1/cyclin B, cdk2/cyclin A, cdk2/cyclin E, and cdk5/p35 respectively. Inhibits ERK1 (IC 50 = 12.0 μ M) and ERK2 (IC 50 = 3.1 μ M) and is 3000-fold selective over a range of other protein kinases (IC 50 > 100 μ M). Arrests cell cycle at G 2 /M boundary (IC 50 = 1.25 μ M), and induces apoptosis at concentrations > 10 μ M. |
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| AMINOPURVALANOL A Upstream-Materialien And Downstream Produkte |
Upstream-Materialien
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Downstream Produkte
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| AMINOPURVALANOL A Anbieter Lieferant Produzent Hersteller Vertrieb Händler. Global( 8)Lieferanten |
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