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CAS-Nr. | 126602-89-9 |
Bezeichnung: | |
Englisch Name: | Quinupristin-dalfopristin |
Synonyma: | SYNERCID;Quinupristin-dalfopristin;Quinupristin-Dalfopristin Mesylate coMplex;Synercid coMplex, Dalfopristin-Quinupristin coMplex |
CBNumber: | CB11252296 |
Summenformel: | C53H67N9O10S.C34H50N4O9S |
Molgewicht: | 1713.09 |
MOL-Datei: | 126602-89-9.mol |
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Quinupristin-dalfopristin physikalisch-chemischer Eigenschaften |
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Quinupristin-dalfopristin Chemische Eigenschaften,Einsatz,Produktion Methoden |
Verwenden Quinupristin-dalfopristin mesylate complex is a 70:30 (w/w) complex of two semi-synthetic analogues marketed as SynercidTM. Dalfopristin is a semisynthetic analogue of virginiamycin M, while quinupristin is a semi-synthetic analogue of virginiamycin B. To optimise stability, the compounds are presented as the mesylate salts with 10% sodium mesylate excess to provide a buffered aqueous solution. The complex is more hydrophobic than the naturally-occurring virginiamycin complex, with a readily ionisable group for generating a salt for improved solubility. There is little published data on the synthesis and biological activity of individual components of the complex, however the combination is a highly effective antibiotic, including activity against resistant strains. |
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Verwenden Quinupristin-dalfopristin mesylate complex is a 70:30 (w/w) complex of two semi-synthetic analogues marketed as Synercid. Dalfopristin is a semisynthetic analogue of virginiamycin M, while quinupristin is a semi-synthetic analogue of virginiamycin B. To optimise stability, the compounds are presented as the mesylate salts with 10% sodium mesylate excess to provide a buffered aqueous solution. The complex is more hydrophobic than the naturally-occurring virginiamycin complex, with a readily ionisable group for generating a salt for improved solubility. There is little published data on the synthesis and biological activity of individual components of the complex, however the combination is a highly effective antibiotic, including activity against resistant strains. |
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Quinupristin-dalfopristin Upstream-Materialien And Downstream Produkte |
Upstream-Materialien
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Downstream Produkte
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Quinupristin-dalfopristin Anbieter Lieferant Produzent Hersteller Vertrieb Händler. Global( 4)Lieferanten |
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