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Quinupristin-dalfopristin Produkt Beschreibung

CAS-Nr.126602-89-9
Bezeichnung:
Englisch Name:Quinupristin-dalfopristin
Synonyma:
SYNERCID;Quinupristin-dalfopristin;Quinupristin-Dalfopristin Mesylate coMplex;Synercid coMplex, Dalfopristin-Quinupristin coMplex
CBNumber:CB11252296
Summenformel:C53H67N9O10S.C34H50N4O9S
Molgewicht:1713.09
MOL-Datei:126602-89-9.mol
Quinupristin-dalfopristin physikalisch-chemischer Eigenschaften
Sicherheit

Quinupristin-dalfopristin Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden
Quinupristin-dalfopristin mesylate complex is a 70:30 (w/w) complex of two semi-synthetic analogues marketed as SynercidTM. Dalfopristin is a semisynthetic analogue of virginiamycin M, while quinupristin is a semi-synthetic analogue of virginiamycin B. To optimise stability, the compounds are presented as the mesylate salts with 10% sodium mesylate excess to provide a buffered aqueous solution. The complex is more hydrophobic than the naturally-occurring virginiamycin complex, with a readily ionisable group for generating a salt for improved solubility. There is little published data on the synthesis and biological activity of individual components of the complex, however the combination is a highly effective antibiotic, including activity against resistant strains.
Verwenden
Quinupristin-dalfopristin mesylate complex is a 70:30 (w/w) complex of two semi-synthetic analogues marketed as Synercid. Dalfopristin is a semisynthetic analogue of virginiamycin M, while quinupristin is a semi-synthetic analogue of virginiamycin B. To optimise stability, the compounds are presented as the mesylate salts with 10% sodium mesylate excess to provide a buffered aqueous solution. The complex is more hydrophobic than the naturally-occurring virginiamycin complex, with a readily ionisable group for generating a salt for improved solubility. There is little published data on the synthesis and biological activity of individual components of the complex, however the combination is a highly effective antibiotic, including activity against resistant strains.
Quinupristin-dalfopristin Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
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126602-89-9(Quinupristin-dalfopristin)Verwandte Suche:
Virginiamycin S1 1-Butyl-4-piperidon
126602-89-9 Quinupristin-dalfopristin SYNERCID Quinupristin-Dalfopristin Mesylate coMplex Synercid coMplex, Dalfopristin-Quinupristin coMplex
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