N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonaMide Produkt Beschreibung

N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonaMide Struktur

CAS-Nr.	918504-65-1
Bezeichnung:
Englisch Name:	N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonaMide
Synonyma:	R7204;PLX4032 (VeMurafenib);Zelboraf (vemurafenib);VeMurafenib (PLX4032, RG7204);PLX4032, R7204, RG7204, RO5185426;N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonaM;N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonaMide;N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide Vemurafenib PLX 4032
CBNumber:	CB02550000
Summenformel:	C23H18ClF2N3O3S
Molgewicht:	489.9221264
MOL-Datei:	918504-65-1.mol

N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonaMide physikalisch-chemischer Eigenschaften

Dichte:

1.46

Sicherheit

N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonaMide Chemische Eigenschaften,Einsatz,Produktion Methoden

Chemische Eigenschaften
Off-White Solid

Verwenden
Vemurafenib selective BRAFV600E kinase inhibitor; an antitumor agent. Vemurafenib functions by inhibiting the proliferation and mitogen-activated protein/extracellular signal-regulated kinase (ERK) kinase and ERK phosphorylation in a panel of tumor cell lines, including melanoma cell lines expressing BRAFV600E or other mutant BRAF proteins altered at codon 600.

Verwenden
Vemurafenib (PLX4032, RG7204) is a novel and potent inhibitor of B-RafV600E with IC50 of 31 nM

N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonaMide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonaMide Anbieter Lieferant Produzent Hersteller Vertrieb Händler. Global( 80)Lieferanten

Firmenname	Telefon	Fax	E-Mail	Land	Produktkatalog	Edge Rate
Shanghai Boyi Chemical Industry Co., Ltd.	+86-21-54380268,	+86-21-54380269	sales@byichem.com	CHINA	34	55
JinYan Chemicals(ShangHai) Co.,Ltd.	13817811078,021-50426030	86-021-50426522,50426273	sales@jingyan-chemical.com	CHINA	10108	60
Jinan Trio PharmaTech Co., Ltd.	+86 (531) 88811793；+86 (531) 88811783;+(0)18854807083;	+86 (531) 55696010 QQ981200479	sales@trio-pharmatech.com (International market);trio@trio-pharmatech.com(Domestic market)	CHINA	1779	62
ShangHai YingYi Chemical Technology Co., Ltd.	86-21-50700185 13764109623	86-21-50700185	sale@inyelchem.com	CHINA	179	55
HangZhou YuHao Chemical Technology Co., Ltd.	0571-82693216	0571-82880190	info@yuhaochemical.com	CHINA	1918	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885	021-65675885	info@efebio.com	CHINA	2042	58
Shanghai Boyle Chemical Co., Ltd.	Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)	86-21-57758967	sales@boylechem.com	CHINA	5604	55
J & K SCIENTIFIC LTD.	--	--	jkinfo@jkchemical.com;market3@jkchemical.com	CHINA	96847	76
PharmaBlock R&D Co. Ltd.	400 025 5188	86-025-86918232	sales_china@pharmablock.com	CHINA	5369	55
ZHIWE CHEMTECH CO LTD	021-20221225;13917446399；QQ:2381298399		sales@zhiwe.net;zwchem@163.com	CHINA	297	61

918504-65-1(N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonaMide)Verwandte Suche:

918504-65-1 N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonaMide Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals Protein Kinase Inhibitors and Activators Sulfur & Selenium Compounds PLX4032 (VeMurafenib) R7204 API Inhibitor N-(3-(5-(4-Chlorophenyl)-1H-pyrrolo[2,3-B]pyridine-3-carbonyl)-2,4-difluorophenyl)propane-1-sulfonaM RG7204 PLX4032, R7204, RG7204, RO5185426 Antineoplastic VeMurafenib (PLX4032, RG7204) N-[3-[[5-(4-Chlorophenyl)-1H-pyrrolo[2,3-b]pyridin-3-yl]carbonyl]-2,4-difluorophenyl]-1-propanesulfonamide Vemurafenib PLX 4032 Zelboraf (vemurafenib)