Company Name: | Shanghai Boyle Chemical Co., Ltd. |
Tel: | Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market) |
Email: | sales@boylechem.com |
Products Intro: |
Product Name:MK2206 CAS:1032350-13-2
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Company Name: | J & K SCIENTIFIC LTD. |
Tel: | 400-666-7788 +86-10-82848833 |
Email: | jkinfo@jkchemical.com;market3@jkchemical.com |
Products Intro: |
Product Name:MK-2206 Dihydrochloride CAS:1032350-13-2 Package:50Mg,5Mg |
Company Name: | PharmaBlock R&D Co. Ltd. |
Tel: | 400 025 5188 |
Email: | sales_china@pharmablock.com |
Products Intro: |
Product Name:MK-2206 dihydrochloride CAS:1032350-13-2 Purity:97% HPLC Package:1GR;10GR;50GR;100GR;250GR;500GR;1KG;5KG;10KG |
Company Name: | Shanghai Science Bio-Pharmaceutical Co. Ltd. |
Tel: | 021-57872719,13918702962/13482412995 |
Email: | market@freefluor.com |
Products Intro: |
Product Name:MK-2206 CAS:1032350-13-2 Purity:HPLC99.9% Package:5Mg;10Mg;25Mg;50Mg |
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| MK-2206 2HCl Basic information |
Product Name: | MK-2206 2HCl | Synonyms: | MK-2206;8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride;MK-2206 Dihydrochloride;8-[4-(1-AMinocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one Hydrochloride;MK-2206 2HCl;8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one;8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride MK-2206;MK-2206 8-[4-(1-Aminocyclobutyl)phenyl]-9-phenyl-1,2,4-triazolo[3,4-f][1,6]naphthyridin-3(2H)-one dihydrochloride | CAS: | 1032350-13-2 | MF: | C25H21N5O | MW: | 407.46714 | EINECS: | | Product Categories: | Amines;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;Inhibitor;PI3K/Akt/mTOR | Mol File: | 1032350-13-2.mol | |
| MK-2206 2HCl Chemical Properties |
| MK-2206 2HCl Usage And Synthesis |
Usage | A highly selective inhibitor of Akt. Akt1, IC50=8 nM; Akt2, IC50=12 nM; Akt3, IC50=65 nM. | Usage | AZD 6244 and MK 2206 are targeted small-molecule drugs that inhibit MEK and AKT responses. The combination of AZD6244 and MK2206 has a significant synergistic effect on tumor growth in vitro and in vi
vo and leads to increased survival rates in mice bearing highly aggressive human lung tumors. Antitumor agents. |
| MK-2206 2HCl Preparation Products And Raw materials |
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