| Company Name: | Suzhou Yacoo Chemical Reagent Corporation Gold |
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| Products Intro: |
Product Name:Guanidine hydrochloride
CAS:50-01-1
Purity:99% Package:25KG;5KG;1KG |
| Company Name: | MP Biomedicals Gold |
| Tel: | 400-1500-680 021-62402299 |
| Email: | nancy.cai@mpbio.com |
| Products Intro: |
Product Name:GUANIDINE HYDROCHLORIDE
CAS:50-01-1
Package:250g,1kg,5KG Remarks:0219482692 |
| Company Name: | Nanjing Search Biotech Co., Ltd Gold |
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| Products Intro: |
Product Name:Guanidine hydrochloride
CAS:50-01-1
Purity:≥99.5% Package:25KG |
| Company Name: | J & K SCIENTIFIC LTD. |
| Tel: | 400-666-7788 +86-10-82848833 |
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| Products Intro: |
Product Name:Guanidine hydrochloride
CAS:50-01-1
Purity:99% Package:100G,25G,500G |
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| | Guanidine hydrochloride Chemical Properties |
| mp | 180-185 °C(lit.)
| | density | 1.18 g/mL at 25 °C(lit.)
| | refractive index | n20/D 1.465
| | storage temp. | Store at RT. | | solubility | H2O: 6 M, clear, colorless
| | Water Solubility | 2280 g/L (20 ºC) | | Sensitive | Hygroscopic | | Merck | 14,4562 | | BRN | 3591990 | | Stability: | Stable. Hygroscopic. Incompatible with strong oxidizing agents. | | CAS DataBase Reference | 50-01-1(CAS DataBase Reference) | | EPA Substance Registry System | Guanidine, monohydrochloride(50-01-1) |
| | Guanidine hydrochloride Usage And Synthesis |
| Application | Guanidine hydrochloride is used in RNA isolation to dissociate nucleoproteins and inhibit RNase.
Strong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.
| | Drug intermediates | Guanidine hydrochloride drug used primarily as an intermediate in the manufacture of sulfadiazine, an important raw material sulfamethyldiazine, sulfamethazine and folic acid.
Guanidine hydrochloride (or guanidine nitrate) and ethyl cyanoacetate reaction, cyclization of 2,4-diamino-6-hydroxy pyrimidine, folic acid for the synthesis of antianemic. Furthermore guanidine hydrochloride also used synthetic anti-static agent.
| | Preparation | In Dicyanodiamide and ammonium (Ammonium chloride) as raw material, melt reaction at 170-230 ℃, guanidine hydrochloride obtained crude, refined products.
| | Chemical Properties | White cryst. powder | | Usage | cholinergic | | Usage | Guanidine has a good bacterial and fungicidal efficacy when used in low concentration and can also be used as disinfectant. |
| | Guanidine hydrochloride Preparation Products And Raw materials |
| Preparation Products | 2-Aminopyrimidine-->5-Amino-2-chloropyrimidine-->2,5-Diamino-4,6-dichloropyrimidine-->7-(TRIFLUOROMETHYL)-3-IODOIMIDAZO[1,2-A]PYRIMIDINE-->3-Bromo-7-(trifluoromethyl)imidazo[1,2-a]pyrimidine-->5-AMINO-2-FLUOROPYRIMIDINE-->2-Chloro-5-nitropyrimidine-->9-ETHYLGUANINE-->Guanidine carbonate-->FORMAMIDINE HYDROCHLORIDE-->2-Amino-5-pyrimidinecarboxyaldehyde-->ISOXANTHOPTERIN-->2-AMINO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER-->2-Aminopyrimidine-5-carboxylic acid-->2-AMINO-6-HYDROXY-PYRIMIDINE-4-CARBOXYLIC ACID-->2-Amino-5-nitropyrimidine-->2-Amino-4-chloro-6-methylpyrimidine-->2-amino-6-chloropyrimidin-4(3H)-one-->GUANINE SULFATE-->2,4-DIAMINO-1,3,5-TRIAZINE-->2-Amino-6-methyl-4-pyrimidinol-->Amiloride hydrochloride-->2-Amino-6-hydroxypyrimidin-4(3H)-one ,97%-->2,4-Diaminopyrimidine-->shark soft bone preparation-->6-HYDROXY-2,4,5-TRIAMINOPYRIMIDINE-->Guanidine phosphate | | Raw materials | Ammonium chloride |
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