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| CAS番号. | 193079-69-5 |
| 化学名: | |
| 别名: | |
| 英語化学名: | Tabimorelin |
| 英語别名: | Tabimorelin;Unii-L51cbe03kf;Tabimorelin [inn];N-[(2E)-5-Amino-5-methyl-1-oxo-2-hexenyl]-N-methyl-3-(2-naphthalenyl)-D-alanyl-N,Nα-dimethyl-D-phenylalaninamidehemifumarate |
| CBNumber: | CB31074328 |
| 分子式: | 2C32H40N4O3.C4H4O4 |
| 分子量: | 1173.46 |
| MOL File: | 193079-69-5.mol |
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Tabimorelin 化学特性,用途語,生産方法 |
使用
NN703 (Tabimorelin) is an orally active growth hormone (GH) secretagogue intended for use as an alternative to daily injections of GH. In vitro studies in human liver microsomes have indicated that NN703 is a mechanism-based inhibitor of CYP3A4. |
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生物活性
Potent, orally active ghrelin receptor (GHS-R1a) agonist (K i = 50 nM at human recombinant GHS-R1a). Stimulates GH release from rat pituitary cells with an EC 50 value of 2.7 nM. Induces hyperphagia and adiposity in lean rats, but not in leptin signaling-deficient ZDF rats. |
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| Tabimorelin 上流と下流の製品情報 |
原材料
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準備製品
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| Tabimorelin 生産企業 Global( 8)Suppliers |
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