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Paclitaxel

CAS No.33069-62-4
Chemical Name:Paclitaxel
Synonyms:taxal;TAXOL;EMPAC;Onxal;TAXUS;Capxol;NK 105;taxol a;ABI 007;DHP 107
CBNumber:CB3273425
Molecular Formula:C47H51NO14
Formula Weight:853.91
MOL File:33069-62-4.mol
Paclitaxel Property
mp : 213 °C (dec.)(lit.)
refractive index : -49 ° (C=1, MeOH)
storage temp. : 2-8°C
solubility : methanol: 50 mg/mL, clear, colorless
form : powder
color : white
Merck : 6982
Stability:: Stable. Incompatible with strong oxidizing agents. Combustible.
CAS DataBase Reference: 33069-62-4(CAS DataBase Reference)
EPA Substance Registry System: Benzenepropanoic acid, .beta.-(benzoylamino)-.alpha.- hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S, 12aR,12bS)-6,12b-bis(acetyloxy)- 12-(benzoyloxy)-2a,3,4,4a, 5,6,9,10,11,12,12a,12b-dodecahydro- 4,11-dihydroxy-4a,8,13,13- tetramethyl-5-oxo-7,11-methano- 1H-cyclodeca[3,4]benz[1,2- b]oxet-9-yl ester, (.alpha.R,.beta.S)-(33069-62-4)
Safety
Hazard Codes : Xn
Risk Statements : 37/38-41-42/43-62-68-40-48-20/21/22-68/20/21/22
Safety Statements : 22-26-36/37/39-45
RIDADR : 1544
WGK Germany : 3
RTECS : DA8340700
F : 10-21
HazardClass : 6.1(b)
PackingGroup : III
Hazardous Substances Data: 33069-62-4(Hazardous Substances Data)

Paclitaxel Chemical Properties,Usage,Production

Chemical Properties
White Powder
Usage
glucocorticoid, antiinflammatory
Usage
An antineoplastic. Used in the study of structure and function of microtubles into tubulin. Paclitaxel is now used to treat patients with lung, ovarian, breast cancer, head and neck cancer, and advanc ed forms of Kaposi's sarcoma. Paclitaxel is a mitotic inhibitor used in cancer chemotherapy.
General Description
Needles (from aqueous methanol) or fine white powder. An anti-cancer drug.
Air & Water Reactions
May be sensitive to prolonged exposure to moisture. .
Health Hazard
TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.
Fire Hazard
Flash point data for Paclitaxel are not available. Paclitaxel is probably combustible.
Biological Activity
Antitumor agent; promotes and stabilizes tubulin polymerization, causing cell cycle arrest. Induces autocatalytic activation of caspase-10 in CCRF-HSB-2 cells, triggering apoptosis.
Paclitaxel Preparation Products And Raw materials
Raw materials
Silica gel Ethyl acetate Celite
Preparation Products
Paclitaxel Suppliers      Global( 387)Suppliers     
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Suzhou Pharmaceutical Technology co.,ltd 400-000-6498051282177481info@fmyykj.comCHINA 94 61
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Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969020-39119999isunpharm@qq.com, isunpharm@hotmail.comCHINA 4836 55
BioBioPha Co., Ltd. +86-871-65217109 QQ: 1020188433+86-871-65215563y.liu@mail.biobiopha.comCHINA 2997 65
Kono Chem Co.,Ltd 86-29-88770941，8132464186-29-81330164sales1@konochemical.comCHINA 508 55
Beijing NuoqiYa Biotechnology Co., Ltd. 4000-819-385 010-62329685 13718666987010-62340519good@nuoqiya.comCHINA 1978 55
Shanghai Aspire Biological Technology Co., Ltd. 021-61317773021-61486878sales@aspirebio.comCHINA 4812 58
Shanghai Boyle Chemical Co., Ltd. Mr Qiu 86-21-50182298(Domestic Market)Miss Xu 86-21-50180596(Abroad Market)86-21-57758967sales@boylechem.comCHINA 5604 55
J & K SCIENTIFIC LTD. ----jkinfo@jkchemical.com;market3@jkchemical.comCHINA 96847 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-59487313(Beijing)+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing)sh@meryer.comCHINA 40407 62
 
33069-62-4(Paclitaxel)Related Search:
Irinotecan Irinotecan hydrochloride polyglutamic acid-paclitaxel PACLITAXEL SOLUTION STD 0.5mg/mL(P) paclitaxel-transferrin (-)-Paclitaxel-2''-hemisuccinate 6a-Hydroxy Paclitaxel-d5 SIDE CHAINS OF PACLITAXEL--3 poly(ethylene glycol)-conjugated paclitaxel-2'-glycinate XYLOSYLTAXOL PACLITAXEL-[BENZOATE RING-UL-14C] 7-(2',3''-DIHYDROXYPROPYL CARBONOXY)PACLITAXEL 6a-Hydroxy Paclitaxel PACLITAXEL C13 LABELED PACLITAXEL, [2-BENZOYL RING-14C(U)] PACLITAXEL-D5 3'-P-HYDROXYTAXOL XYLOSYLTAXOL, 7
N-BENZYL-BETA-PHENYLISOSERINE ESTER PACLITAXEL, TAXUS BREVIFOLIA PACLITAXEL, TAXUS SPECIES PACLITAXOL PACLITAXEL TAXOL(TM) taxol a TAXOL EQUIVALENT TAXOL(R) TAXOL taxal BACCATIN III N-BENZYL-BETA-PHENYLISOSERINE ESTER BACCATIN III 33069-62-4 BioChemical Antibiotics Antibiotics N-S Antibiotics A to Z 7,11-methano-5h-cyclodeca[3,4]benz[1,2-b]oxete benzenepropanoic acid deriv. [2ar-[2aalpha,4beta,4abeta,6beta,9alpha(alphar*,betas*),11alpha,12alpha,12bal -12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4 12a-alpha,12b-alpha))-12-alpha 4,10-diacetate2-benzoate13-esterwith(2r,3s)-n-benzoyl-3-phenylisoserine 5beta,20-epoxy-1,2alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one -9-ylester a,8,13,13-tetramethyl-5-oxo-7,11-methano-1h-cyclodeca(3,4)benz(1,2-b)oxet-9-y benzenepropanoicacid,beta-(benzoylamino)-alpha-hydroxy-,6,12b-bis(acetyloxy) bms181339-01 lester,(2ar-(2a-alpha,4-beta,4a-beta,6-beta,9-alpha(alpha-r*,beta-s*),11-alph nsc125973 nsc-125973 oxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydr oxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1h-cyclodeca[3,4]benz[1,2-b]oxet peclitaxel pha]]-beta-(benzoylamino)-alpha-hydroxybenzenepropanoicacid6,12b-bis(acetyl Paclitaxe PACLITAXEL FROM TAXUS BREVIFOLIA PACLITAXEL FROM TAXUS YANNANENSIS SEMI-SYMTHETIC PACLITAXEL (NON-CELL- CUL TURE) PACLITAXEL, 99% NATURAL PACLITAXEL, RELATED COMPOUND B10-DEACETYL-7-EPIPACLITAXEL, USP STANDARD PACLITAXEL, 99.5+% NATURAL PACLITAXEL, 1% PLANT EXTRACT PACLITAXEL, RELATED COMPOUND ABENZENE PROPANOIC ACID, ALPHA-HYDROXY-BETA-((2-METHYL-1-OXO-2-BUTENYL)AMINO)-, 6,12B-BIS(ACETYLOXY)-12-(BENZOYLOXY)-2A,3,4,4A,5,6,9,10,11,12,12A,12B-DODECAHYDRO-4,11-DIHYDROXY-4A,8,13,13-TETRAMETHYL-5-OXO-7,11-METHANO-1H-CYLC PACLITAXEL, USP STANDARD PACLITAXEL, 99% SYNTHETIC PACLITAXEL, 50% PLANT EXTRACT Paclitaxel(Taxol)99.5% C47H51NO14 Paclitaxel, 99+% Benzenepropanoic acid, b-(benzoylamino)-a-hydroxy-, (2aR,4S,4aS,6R,9S,11S,12S,12aR,12bS)-6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tet ramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-yl ester, (aR,bS)- Paclitaxel Natural NATURAL PACLITAXEL SEMI-SYNTHETICAL PACLITAXEL PACLITAXEL(P) Paclitaxol(taxol) Active Pharmaceutical Ingredients Pharmaceutical material and intermeidates
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