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CAS-Nr. | 111470-99-6 |
Bezeichnung: | |
Englisch Name: | Amlodipine besilate |
Synonyma: | Amlor;Amcard;Lowrac;Norvas;Vazkor;NORVASC;Amdepin;Amdipin;Amlodin;Amlopin |
CBNumber: | CB4127875 |
Summenformel: | C26H31ClN2O8S |
Molgewicht: | 567.05 |
MOL-Datei: | 111470-99-6.mol |
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Amlodipine besilate physikalisch-chemischer Eigenschaften |
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storage temp. : |
Store at RT |
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solubility : |
DMSO: 20 mg/mL
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Amlodipine besilate Chemische Eigenschaften,Einsatz,Produktion Methoden |
Chemische Eigenschaften White Crystalline Solid |
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Verwenden A dihydropyridine calcium channel blocker. Used as an antianginal and antihypertensive |
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Verwenden Angiotensin II inhibitor prodrug, antihypertensive |
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Verwenden Amlodipine besylate is a L-type calcium channel blocker which may be used for the treatment of angina pectoris and hypertension. Amlodipine also inhibits growth of human epidermoid carcinoma A431 cells and has antireproductive effects in male rats. |
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R-Sätze Betriebsanweisung: R22:Gesundheitsschädlich beim Verschlucken. R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut. R20/21/22:Gesundheitsschädlich beim Einatmen,Verschlucken und Berührung mit der Haut. |
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S-Sätze Betriebsanweisung: S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren. S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen. |
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Biologische Aktivit?t L-type calcium channel blocker that displays antihypertensive properties. Inhibits Ca 2+ -induced contractions in depolarized rat aorta (IC 50 = 1.9 nM) and displays vasoprotective effects in cardiovascular disease. Inhibits proliferation of human vascular smooth muscle cells and epidermoid carcinoma A431 cells (IC 50 = 25 μ M). |
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Amlodipine besilate Upstream-Materialien And Downstream Produkte |
Upstream-Materialien
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Downstream Produkte
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Amlodipine besilate Anbieter Lieferant Produzent Hersteller Vertrieb Händler. Global( 214)Lieferanten |
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2-[(2-AMINOETHOXY)-METHYL]-4-(2-CHLOROPHENYL)-1,4-DIHYDRO-6-METHYL-3,5-PYRIDINEDICARBOXYLIC ACID 3-ETHYL 5-METHYL ESTER BENZENE SULFONATE
2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine benzenesulfonate
111470-99-6
Cell Signaling and Neuroscience
Calcium Channel Modulators
Cell Biology
BioChemical
AMLODIPINE BENZENESULFONATE
AMLODIPINE BESILATE
AMLODIPINE BESYLATE
NORVASC
Ion Channels
Inhibitors and Activators
Voltage-gated Ion Channels
3,5-pyridinedicarboxylicacid,2-((2-aminoethoxy)methyl)-4-(2-chlorophenyl)-1,
4-dihydro-6-methyl-,3-ethyl-5-methylester,monobenzenesulfonate
AMLODIPINE BESILATE MM(CRM STANDARD)
AMLODIPINE BESYLATE EPY(CRM STANDARD)
C20H25ClN2O5C6H6O3S
11470-99-6
2-[(2-aminoethoxy)-methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester benzene sulfonate
AMLODIPINEBESYLATE(SUBJECTTOPATENTFREE)
(+-)-3-Ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate monobenzenesulfonate
3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester, monobenzenesulfonate
Amcard
Amdepin
Amdipin
Amlodin
Amlopin
Amlor
Amlosyn
Antacal
Benzenesulfonic acid, compd. with 3-ethyl 5-methyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-3,5-pyridinedicarboxylate (1:1)
Calchek
Lowrac
Monopina
Norvas
Norvask
Tensivask
UK 48340-26
C26H31ClN2O8S
Active Pharmaceutical Ingredients
2-[(2-Aminoethoxy)methyl]-4-(2-chlorophenyl)-3-ethoxycarbonyl-5-methoxycarbonyl-6-methyl-1,4-dihydropyridine benzenesulfonate
Ethyl 2-[(2-aminoethoxy)methyl]-4-(2-chloropohenyl)-1,4-dihydro-5-(methoxycarbonyl)-6-methylpyridine-3-carboxylate benzenesulphonate
Dihydropyridine Class Chemicals
Intermediates & Fine Chemicals
Pharmaceuticals
Amlodipine
2-(2-Aminoethoxymethyl)-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3-ethyl=5-methyl·benzenesulfonic acid
C20H25ClN2O5C6H5SO3H
Aromatics
Dihydropyridine
Heterocycles
111470-99-6
Amlodipine Besylate (350 mg)
Vazkor
3-Ethyl 5-Methyl 2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate Benzenesulfonate
2-(2-Aminoethoxy)methyl-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylic Acid 3-Ethyl 5-Methyl Ester Benzenesulfona
3-ethyl 5-Methyl 2-((2-aMinoethoxy)Methyl)-4-(2-chlorophenyl)-6-Methyl-1,4-dihydropyridine-3,5-dicarboxylate benzenesulfonate
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